Main description:

History of Immunotoxicology offers the first book-length exploration of the development and importance of the field of immunotoxicology, describing the adverse health effects involving the immune system, hypersensitivity and autoimmunity. It explores new avenues of research and immunotoxicity evaluation, regulatory aspects of immunotoxicology, and the withdrawal/banning from the market of several approved drugs and chemicals due to their immunotoxic effects. In addition, clinical manifestations of immunotoxicity, such as anaphylaxis, opportunistic infections, lymphomas, cytokine storm, and immunotherapy are addressed. Finally, the book considers how the recent past can provide insights on the future practice of immunotoxicology.

As preventive measures are implemented to reduce risks, including banning of chemicals or applications of one given chemical, current toxicologists may not be aware of the toxicity potential of chemicals. This book will be of interest to students and researchers in government, industry and academia who have an interest in immunotoxicology.

Contents:

1. The prehistory of immunotoxicology
2. Focus on autoimmunity and hypersensitivity
3. Clinical immunotoxic effects
4. Drug withdrawals caused by inacceptable immunotoxicity
5. Pioneering inter-laboratory studies
6. Regulatory aspects of immunotoxicology
7. Immunotherapy of poisonings
8. Insights on the future of immunotoxicity evaluation