Main description:

This detailed book serves to provide a global overview of the goals, rationale, and scientific basis for malaria control and elimination, as well as tools, methods, and strategies to that end. Opening with a section on malaria epidemiology, the volume continues by covering tools that are critical to malaria management, anti-malarial drugs and resistance to these drugs, vaccination approaches against malaria, vector control, as well as some perspective on the future of the fight against this devastating disease. Written for the highly successful Method in Molecular Biology series, chapters in this collection feature the kind of practical, hands-on advice that leads to better results in the field.
Authoritative and important, Malaria Control and Elimination is a valuable reference for all those involved in malaria control and elimination worldwide, from students to health practitioners and field researchers seeking to make eradication a reality wherever possible.

Contents:

Part I: Epidemiology

1. Country-Owned, Country-Driven: Perspectives from the World Health Organization on Malaria Elimination

Kim A. Lindblade, Li Xiao Hong, Gawrie Loku Galappaththy, Abdisalan Noor, Jan Kolaczinski, and Pedro L. Alonso

2. Current Situation of Malaria in Africa

Wilfred Fon Mbacham, Lawrence Ayong, Magellan Guewo-Fokeng, and Valerie Makoge

3. Current Malaria Situation in Asia-Oceania

Chansuda Wongsrichanalai, Rossitza Kurdova-Mintcheva, and Kevin Palmer

4. Malaria Situation in Latin America and the Caribbean: Residual and Resurgent Transmission and Challenges for Control and Elimination

Marcelo U. Ferreira and Marcia C. Castro

Part II: Methods

5. Diagnosing Malaria: Methods, Tools, and Field Applicability

Lawrence Ayong, Carole Eboumbou, and Wilfred F. Mbacham

6. Serological Profiling for Malaria Surveillance Using a Standard ELISA Protocol

Linda M. Murungi, Rinter K. Kimathi, James Tuju, Gathoni Kamuyu, and Faith H.A. Osier

7. Controlled Human Malaria Infection (CHMI) Studies: Over 100 Years of Experience with Parasite Injections

Kai Matuschewski and Steffen Borrmann

Part III: Therapeutics

8. In Vivo Assessments to Detect Antimalarial Resistance

Mehul J. Dhorda and Adrianus M. Dondorp

9. Plasmodium falciparum In Vitro Drug Resistance Selections and Gene Editing

Caroline L. Ng and David A. Fidock

10. An Update on Artemisinin Resistance

Frederic Ariey and Didier Menard

11. Antimalarial Drugs for Malaria Elimination

Jerome Clain, Abderaouf Hamza, and Frederic Ariey

Part IV: Vaccinology

12. Vaccine Development: From Preclinical Studies to Phase 1/2 Clinical Trials

Cecile Artaud, Leila Kara, and Odile Launay

13. The Advanced Development Pathway of the RTS,S/AS01 Vaccine

Lorenz von Seidlein

14. Live Vaccines against Plasmodium Pre-Erythrocytic Stages

Laura Mac-Daniel and Robert Menard

15. Development of Blood Stage Malaria Vaccines

Aneesh Vijayan and Chetan E. Chitnis

Part V: Vector Control

16. Insecticide-Treated Mosquito Nets

Pierre Carnevale and Frederick Gay

17. Sampling Adult Populations of Anopheles Mosquitoes

Julie-Anne A. Tangena, Alexandra Hiscox, and Paul T. Brey

18. Insecticides and Insecticide Resistance

Mamadou Ousmane Ndiath

Part VI: Opinions

19. Herbal Remedies to Treat Malaria in Madagascar: Hype and Hope

Arsene Indriambelo, Mamy Arilandy Rakotomamonjy, Rakotondrafara Andriamalala, Harison Rabarison, Michel Ratsimbason, Astrid Knoblauch, and Milijaona Randrianarivelojosia

20. Vade Retro Malaria: The Vagaries of Eradication Campaigns

Georges Snounou