Main description:

This concise, clinically focused pocket guide offers a complete overview of HIV in the older patient and reviews the latest guidelines, treatment options, clinical trials, and management of HIV within this subgroup. The easily accessible text offers infectious disease specialists and other health care professionals with an excellent quick reference tool, with full color tables and figures enhancing the text further. HIV is a chronic disease that affects the immune system, leading to AIDS. As treatments have progressed and patients with HIV are living longer a new aspect has to be taken in to consideration when treating HIV and other conditions. Comorbidities are rife within older adults with HIV, as many of the treatments for HIV cause long-term side effects, such as heart conditions and cancer. Special consideration must be taken to ensure no toxic drug-drug interactions between treatments.

Contents:

1. Introduction

References

2. Pathophysiology of HIV/AIDS

Key points

2.1 Immunodeficiency, immune activation, and chronic inflammation

2.2 HIV and immunosenescence

2.3 Evolving clinical profile

References

3. HIV associated non-AIDS conditions in patients aging with HIV

Key points

3.1 HIV-associated non-AIDS conditions versus comorbidities

References

4. Comorbid conditions and older adults with HIV

Key points

4.1 Multimorbidity

4.2 Accentuated versus accelerated aging

4.3 Aging versus aged

References

5. Frailty in HIV

Key points

5.1 Defining frailty

5.2 Measuring frailty

5.3 The utility of measuring frailty

5.4 Frailty in the context of HIV

References

6. Disability

Key points

6.1 Overview

6.2 Functional impairment and disability in patients with HIV

6.3 Tools to measure disability

6.4 Conclusion

References

7. Geriatric syndromes

Key points

7.1 Definition

7.2 Falls

7.3. Delirium

7.4 Conclusion

References

8. HIV prevention and screening in older adults

Key points

8.1 Age-related risk factors

8.2. Barriers to prevention

8.3. Screening and counselling opportunities

References

9. Multidimensional geriatric assessment in older patients with HIV

Key points

References

10. Antiretroviral treatment in older patients

Key points

10.1 When to start antiretroviral therapy

10.2 What to start

10.3 What to change

10.4 Future perspectives

References

11. HIV, aging, and polypharmacy

Key points

References

12. Nutrition and physical exercise in older patients with HIV

Key points

12.1 Overview

12.2 Assessment of risk of malnutrition

12.3 Intervention

12.4 Sarcopenic obesity

12.5 Physical exercise

12.6 Conclusion

References

13. Smoking cessation in patients with HIV

Key points

13.1 Pharmacological strategies to treat nicotine dependence

References

14. Self-management

Key points

References