Main description:

Comprehensive Preparation for GAMSAT Section 3: Organic Chemistry
From a very basic, introductory level, up to GAMSAT level with clear teaching

Covers all Organic Chemistry topics ('assumed knowledge') in Section 3 of the GAMSAT: everything from Stereochemistry to Elimination vs. Substitution, as well as exercises and practice questions to improve your geometric reasoning and pattern recognition

Clear teaching with more content as compared to previous editions with new diagrams, illustrations and practice questions in the book.

The book contains foundational (basic understanding) multiple-choice questions (MCQs) followed by GAMSAT-level MCQs completely updated to reflect the most current exam trends.

Contents:

Introduction. ORG-04
GAMSAT ORGANIC CHEMISTRY
Chapter 1. Molecular Structure of Organic Compounds. . . . . . . . . . . . . . . . .ORG-13
1.0 GAMSAT has a Need for Speed!. ORG-14
1.1 Carbon: The Centre of our World. ORG-18
1.1.1 Overview: A Closer Look at the Atoms of Organic Chemistry. . . . .ORG-23
1.2 Hybrid Orbitals. ORG-24
1.3 Bonding. ORG-25
1.3.1 The Effects of Multiple Bonds. ORG-26
1.4 Delocalised Electrons and Resonance. ORG-26
1.5 Lewis Structures, Charge Separation and Dipole Moments. ORG-27
1.5.1 Strength of Polar vs. Non-Polar Bonds. ORG-30
1.6 Ground Rules. ORG-31
1.6.1 Primary, Secondary, Tertiary, and Quaternary
Carbons and Molecules . ORG-33
1.6.2 Exercise: Introduction to Identifying Functional Groups. ORG-33
1.7 Drawing Molecular Structures of Organic Compounds. ORG-35
1.8 Pattern Recognition, Geometric Reasoning and
Problem-based Learning . ORG-41
Chapter 2. Stereochemistry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ORG-59
2.0 GAMSAT has a Need for Speed!. ORG-60
2.1 Isomers. ORG-62
2.1.1 Structural (Constitutional) Isomers. ORG-62
2.2 Spatial/Stereoisomers. ORG-63
2.2.1 Geometric Isomers cis/trans, E/Z. ORG-63
2.2.2 Enantiomers and Diastereomers. ORG-64
2.3 Absolute and Relative Configuration. ORG-65
2.3.1 The R, S System and Fischer Projections . ORG-66
2.3.2 Optical Isomers. ORG-69
2.3.3 Meso Compounds. ORG-70
2.4 Conformational Isomers. ORG-71
Chapter 2: Gold Standard Foundational GAMSAT Practice Questions. ORG-75
Chapter 2: Gold Standard GAMSAT-Level Practice Questions. ORG-76
Chapter 3. Alkanes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ORG-83
3.0 GAMSAT has a Need for Speed!. ORG-84
3.1 Description and Nomenclature. ORG-85
3.1.1 Bicycloalkanes: Examples of Isomeric C8H14 . ORG-87
3.1.2 Foundational Nomenclature Exercises: Alkanes. ORG-87
3.1.3 Physical Properties of Alkanes. ORG-89
-vi3.2
Important Reactions of Alkanes. ORG-89
3.2.1 Combustion. ORG-89
3.2.2 Radical Substitution Reactions. ORG-90
3.3 Ring Strain in Cyclic Alkanes. ORG-91
Chapter 3: Gold Standard GAMSAT-Level Practice Questions. ORG-94
Chapter 4. Alkenes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ORG-99
4.0 GAMSAT has a Need for Speed!. ORG-100
4.1 Description and Nomenclature. ORG-101
4.1.1 Foundational Nomenclature Exercises: Alkenes and Alkynes . ORG-103
4.2 Important Chemical Reactions. ORG-105
4.2.1 Electrophilic Addition. ORG-105
4.2.2 Oxidation. ORG-110
4.2.3 Hydrogenation. ORG-112
4.2.4 The Diels-Alder Reaction. ORG-112
4.2.5 Resonance Revisited . ORG-114
4.3 Alkynes. ORG-115
Chapter 4: Gold Standard Foundational GAMSAT Practice Questions. ORG-117
Chapter 4: Gold Standard GAMSAT-Level Practice Questions. ORG-118
Chapter 5. Aromatics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .ORG-127
5.1 Description and Nomenclature. ORG-128
5.1.1 Huckel's Rule . ORG-129
5.2 Electrophilic Aromatic Substitution. ORG-131
5.2.1 O-P Directors . ORG-133
5.2.2 Meta Directors. ORG-134
5.2.3 Reactions with the Alkylbenzene Side Chain. ORG-135
Chapter 5: Gold Standard Foundational GAMSAT Practice Questions. ORG-136
Chapter 5: Gold Standard GAMSAT-Level Practice Questions. ORG-137
Chapter 6. Alcohols. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ORG-145
6.0 GAMSAT has a Need for Speed!. ORG-146
6.1 Description and Nomenclature. ORG-148
6.1.1 Foundational Nomenclature Exercises: Alcohols. ORG-149
6.1.2 Acidity and Basicity of Alcohols . ORG-150
6.1.3 Synthesis of Alcohols: How to Make Alcohols . ORG-151
6.2 Important Reactions of Alcohols. ORG-153
6.2.1 Dehydration. ORG-153
6.2.2 Oxidation-Reduction. ORG-154
6.2.3 Substitution. ORG-154
6.2.4 Elimination. ORG-156
6.2.5 Conversion of Alcohols to Alkyl Halides. ORG-157
Chapter 6: Gold Standard Foundational GAMSAT Practice Questions. ORG-159
Chapter 6: Gold Standard GAMSAT-Level Practice Questions. ORG-161
GOLD STANDARD GAMSAT ORG-01
Chapter 7. Aldehydes and Ketones. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .ORG-171
7.1 Description and Nomenclature. ORG-172
7.1.1 Foundational Nomenclature Exercises:
Aldehydes and Ketones . ORG-174
7.2 Important Reactions of Aldehydes & Ketones . ORG-175
7.2.1 Overview. ORG-175
7.2.2 Acetal (ketal) and Hemiacetal (hemiketal) Formation. ORG-177
7.2.3 Imine and Enamine Formation . ORG-178
7.2.4 Aldol Condensation. ORG-179
7.2.5 Conjugate Addition to - Unsaturated Carbonyls. ORG-180
Chapter 7: Gold Standard Foundational GAMSAT Practice Questions. ORG-182
Chapter 7: Gold Standard GAMSAT-Level Practice Questions. ORG-184
Chapter 8. Carboxylic Acids. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .ORG-191
8.1 Description and Nomenclature. ORG-192
8.1.1 Foundational Nomenclature Exercises: Carboxylic Acids. ORG-194
8.1.2 Carboxylic Acid Formation . ORG-195
8.2 Important Reactions of Carboxylic Acids . ORG-196
Chapter 8: Gold Standard Foundational GAMSAT Practice Questions. ORG-199
Chapter 8: Gold Standard GAMSAT-Level Practice Questions. ORG-199
Chapter 9. Carboxylic Acid Derivatives . . . . . . . . . . . . . . . . . . . . . . . . . . . . ORG-205
9.1 Acid Halides. ORG-206
9.1.1 Acid Anhydrides . ORG-206
9.2 Important Reactions of Carboxylic Acid Derivatives. ORG-207
9.3 Amides. ORG-209
9.3.1 Important Reactions of Amides. ORG-210
9.4 Esters. ORG-210
9.4.1 Fats, Glycerides and Saponification. ORG-213
9.5 -Keto Acids. ORG-213
9.6 Relative Reactivity of Carboxylic Acid Derivatives. ORG-214
9.7 Phosphate Esters. ORG-214
Chapter 9: Gold Standard Foundational GAMSAT Practice Questions. ORG-215
Chapter 9: Gold Standard GAMSAT-Level Practice Questions. ORG-217
Chapter 10. Ethers and Phenols . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ORG-223
10.1 Description and Nomenclature of Ethers . ORG-224
10.1.1 Important Reactions of Ethers. . . . . . . . . . . . . . . . . . . . . . . . . . . .ORG-224
10.2 Phenols. ORG-226
10.2.1 Electrophilic Aromatic Substitution for Phenols. ORG-227
Chapter 10: Gold Standard Foundational GAMSAT Practice Questions. ORG-228
Chapter 10: Gold Standard GAMSAT-Level Practice Questions. ORG-229
ORG-02 INTRODUCTION TO ORGANIC CHEMISTRY
Chapter 11. Amines. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ORG-235
11.1 Description and Nomenclature. ORG-236
11.1.1 The Basicity of Amines. ORG-237
11.1.2 More Properties of Amines. ORG-238
11.2 Important Reactions of Amines. ORG-239
Chapter 11: Gold Standard Foundational GAMSAT Practice Questions. ORG-242
Chapter 11: Gold Standard GAMSAT-Level Practice Questions. ORG-244
Chapter 12. Biological Molecules . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ORG-251
12.1 Amino Acids. ORG-252
12.1.1 Hydrophilic vs. Hydrophobic. ORG-253
12.1.2 Acidic vs. Basic. ORG-254
12.1.3 The 20 Alpha-Amino Acids. ORG-255
12.2 Proteins. ORG-257
12.2.1 General Principles. ORG-257
12.2.2 Protein Structure. ORG-258
12.2.3 Protein Function and Detection. ORG-261
12.3 Carbohydrates . ORG-261
12.3.1 Description and Nomenclature. ORG-261
12.3.2 Important Reactions of Carbohydrates. ORG-265
12.3.3 Polysaccharides. ORG-268
12.4 Lipids. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .ORG-270
12.4.1 Steroids. ORG-274
12.4.2 Lipoproteins. ORG-275
12.5 Phosphorous in Biological Molecules. ORG-275
Chapter 12: Gold Standard GAMSAT-Level Practice Questions. ORG-277
Chapter 13. Separations and Purifications. . . . . . . . . . . . . . . . . . . . . . . . . . ORG-295
13.1 Separation Techniques. ORG-296
13.2 Chromatography. ORG-298
13.2.1 Gas-Liquid Chromatography. ORG-298
13.2.2 Thin-Layer Chromatography. ORG-298
13.2.3 Paper chromatography: Conventional and 2D . ORG-300
13.2.4 Column Chromatography . ORG-301
13.3 Gel Electrophoresis . ORG-301
13.4 Recrystallisation. ORG-302
Chapter 14. Spectroscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ORG-305
14.1 IR Spectroscopy. ORG-306
14.2 Proton NMR Spectroscopy. ORG-307
14.2.1 Deuterium Exchange. ORG-310
14.2.2 13C NMR. ORG-310
14.3 Mass Spectrometry. ORG-311
GOLD STANDARD GAMSAT ORG-03