Main description:

This book combines medicinal and engineering knowledge to present engineering modelling applications (mainly computational, but also experimental) in the context of facilitating a patient-centred approach to treating congenital heart disease (CHD). After introducing the basic concepts of engineering tools, it discusses modelling and the applications of engineering techniques (e.g. computational fluid dynamics, fluid-structure interaction, structural simulations, virtual surgery, advanced image analysis, 3D printing) in specific congenital heart diseases. It also offers a number of clinical case studies describing the applications in real-life clinical practice. The final section focuses on the importance of surgical training, counselling and patient communication.

Considering the unique anatomical arrangement pre/post repair in CHD, as well as the different surgical strategy and device options (e.g. stents) for interventions, a patient-specific approach is certainly warranted in this area of medicine, and engineering is helping improve our understanding of individual patients and their particular anatomy and physiology.

To reinforce the idea of a necessary dialogue between clinicians and engineers, this book has not only been edited by two cardiologists and two bioengineers, but each chapter has been written by a clinician and an engineer, incorporating both voices in the description of state-of-the-art models for different CHDs.

Contents:

PrefaceForewordPart 1: Basic concepts 1. Overview of computational methods2. Congenital heart diseases: basic concepts from a paediatric cardiology perspectivePart 2: Diseases: modelling and applications3. Septal defects: clinical concepts, engineering applications and impact of an integrated medico-engineering approach --- Occluder devices4. Aortic coarctation: clinical concepts, engineering applications and impact of an integrated medico-engineering approach5. Tetralogy of Fallot, the right ventricular outflow tract. Clinical concepts, engineering applications and impact of an integrated medico-engineering approach6. Tetralogy of Fallot: clinical concepts, engineering applications and impact of an integrated medico-engineering approach - Ventricle7. Complete Transposition of Great Arteries post Arterial Switch Operation: an integrated approach of imaging and modelling to assess long-term outcomes8. Double Outlet Right Ventricle: introductory concepts and applications9. Hypoplastic Left Heart Syndrome: Introductory Concepts10. Hypoplastic left heart syndrome, Norwood and variants: engineering applications and impact of an integrated medico-engineering approach11. Univentricular hearts: clinical concepts and impact of an integrated medico-engineering approach12. Fontan surgery and fluid dynamics13. Ventriculo-arterial coupling in Fontan patients 14. Modelling the pulmonary circulation in CHD: clinical concepts, engineering applications and of an integrated medico-engineering approach15. Modelling pulmonary arterial hypertension: clinical concepts, engineering applications and an integrated medico-engineering approachPart 3: How I used a model in clinical practice 16. Patient-specific numerical modeling to predict coronary artery compression in transcatheter pulmonary valve implantation17. Transcatheter correction of Sinus Venosus Atrial Septal Defect (SVASD) and partial anomalous pulmonary venous drainage with a covered stent18. Modelling the coronary anatomy in a case of suspected Kawasaki disease with giant coronary aneurysms19. Criss cross heart: is biventricular repair ever possible?20. Use of 3D printing for Congenital Heart Disease21. Case Report: Three-dimensional printed model guiding transcutaneous device closure of a complex residual ventricular septal defect: comparing apples to apples22. 3D "modeling" and "printing" in neonate with complex twisted heart: new frontier for clinical decision and optimal surgical approach23. Biventricular Repair of Complex Transposition of Great Arteries Guided by 3D Reconstruction ImagingPart 4: Training, counselling and miscellanea24. Three-Dimensional Printing and its Applications in Education and Teaching25. Dassault Systemes' Living Heart Project26. Cardiovascular simulation as a decision support tool27. Artificial intelligence in Paediatric Cardiology28. Communication in congenital heart disease: a relevant application for engineering models?29. Three Dimensional Multimodality Fusion in Minimally Invasive Congenital Heart Interventions