Main description:

This volume presents a useful and up-to-date handbook containing information relevant to the clinical practice of molecular genetic pathology. It features organized, detailed text on specific molecular genetic techniques. The volume provides a unique reference for the practicing pathologist and medical geneticist, as well as a review book for residents and fellows in training in pathology, medical genetics and molecular genetic pathology.

Contents:

Part I. General Sections Principles of Clinical Molecular Biology Principles of Clinical Cytogenetics Diagnostic Methodology and Technology Tissue Microarrays and Biomarker Validation Laser Capture Microdissection Clinical Flow Cytometry Conceptual Evolution in Cancer Biology Clinical Genomics in Oncology Clinical Proteomics Clinical Pharmacogenomics Clonality Analysis in Modern Oncology and Surgical Pathology Fluorescence in situ Hybridization (FISH) and Conventional Cytogenetics for Hematology and Oncology Diagnosis Instrumentation Genetic Inheritance and Population Genetics Genetic Counseling Part II. Disease-Based Sections Molecular Medical Genetics Prenatal Diagnosis Familial Cancer Syndromes Molecular Testing for Solid Tumors Molecular Pathology of the Central Nervous System Molecular Virology Molecular Bacteriology, Mycology and Parasitology Molecular Testing for Coagulopathies Molecular Hemoglobinopathies Molecular Diagnostics of Lymphoid Malignancies Molecular Diagnostics of Myeloid Leukemias The HLA System and Transfusion Medicine: Molecular Approach Molecular Forensic Pathology Gene Therapy: Vector Technology and Clinical Applications Ethical and Legal Issues in Molecular Testing Quality Assurance and Laboratory Inspection