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Molecular Genetics of Recombination
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Main description:

This work offers a fascinating insight into a crucial genetic process. Recombination is, quite simply, one of the most important topics in contemporary biology. This book is a totally comprehensive treatment of the subject, summarizing all existing views on the topic and at the same time putting them into context. It provides in-depth and up-to-date analysis of the chapter topics, and has been written by international experts in the field.


Contents:

Genetics of Recombination in the Model Bacterium Escherichia Coli.- Homologous Recombination in Low dC + dG Gram-Positive Bacteria.- The Bacterial RecA Protein: Structure, Function, and Regulation.- Biochemistry of Eukaryotic Homologous Recombination.- DNA helicases in recombination.- Holliday Junction Resolution.- Replication forks and replication checkpoints in repair.- Sister chromatid recombination.- Mating-Type Switching in S. Pombe.- Multiple Mechanisms of Repairing Meganuclease-Induced Double-Strand DNA Breaks in Budding Yeast.- The Cell Biology of Mitotic Recombination in Saccharomyces Cerevisiae.- The cell biology of homologous recombination.- BRCA2: safeguarding the genome through homologous recombination.- Meiotic recombination.- Site-specific recombination.- V(D)J Recombination: Mechanism and Consequences.- Nonhomologous End-Joining: Mechanisms, Conservation and Relationship to Illegitimate Recombination.- Analytical methods from the perspective of method standardization.


PRODUCT DETAILS

ISBN-13: 9783642090059
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: November, 2010
Pages: 550
Weight: 820g
Availability: Available
Subcategories: Biochemistry
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