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MORE ABOUT THIS BOOK
Main description:
This book provides an up-to-date and comprehensive overview of protein phosphatase research, a rapidly evolving field with increasing importance in our understanding of the molecular basis of cell biology and of pathological processes.
The book covers dephosphorylation processes involving serine/threonine, as well as tyrosine and histidine residues, and aims to be a useful resource for both the advanced reader as well as the newcomer to the field. It is also valuable for those working in the pharmaceutical and Biotech industries.
Contents:
Overview of Protein Serine/Threonine Phosphatases.- Protein Phosphatase 1.- Protein Phosphatase 2A: A Multifunctional Regulator of Cell Signaling.- Calcineurin: Roles of the Ca2+/Calmodulin-dependent Protein Phosphatase in Diverse Eukaryotes.- Roles of Mammalian Protein Phosphatase 2C Family Members in the Regulation of Cellular Functions.- PP5: the TPR Phosphatase.- Protein Histidine Phosphatases in Signal Transduction and Metabolism.- Anchoring of Protein Kinase and Phosphatase Signaling Units.- Functional Proteomics in Phosphatase Research.- Structure and Function of the T-cell Protein Tyrosine Phosphatase.- Protein Tyrosine Phosphatase-based Therapeutics: Lessons From PTP1B.- The CD45 Phosphotyrosine Phosphatase.- Receptor Protein Tyrosine Phosphatases.- The Shp-2 Tyrosine Phosphatase.- SHP-1 Twelve Years on: Structure, Ligands, Substrates and Biological Roles.- The Dual-specific Protein Tyrosine Phosphatase Family.- Tyrosine Phosphatases in Cancer: Targets for Therapeutic Intervention.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: April, 2011
Pages: 378
Weight: 605g
Availability: Available
Subcategories: Biochemistry, General Issues
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