Main description:

Now in its second edition, this comprehensive handbook provides a state-of-the-art overview of recent advances in drug and non-drug therapies for obesity and diabetes. It also addresses major comorbidities, covering topics such as, cardiovascular diseases, renal and neuropsychiatric disorders, appetite control and micro RNAs. Special attention is also devoted to pediatric care, including the latest recommendations for therapy and prevention.

Obesity and type 2 diabetes are among the top global health-care budget concerns worldwide and impact professional practice at all levels: in hospitals, clinics and physicians' offices alike. They prominently feature in headlines, and virtually no family, community or country is exempt from their protean, deleterious consequences. Furthermore, given the multiple intersections in their pathways, they often go hand in hand.

The good news is that scientific advances in all fields, including genomics, metabolomics, lipidomics and microbiomics, are increasing our understanding of these two disease areas. At the same time, artificial intelligence, machine learning, mobile health and advanced implantable and external devices are rendering prevention and management more available, safe and cost-effective. In addition, bariatric and metabolic surgery has evolved from a niche specialty to an officially endorsed option for several modalities of obesity and diabetes.

This book presents the latest lifestyle, pharmacological, surgical and non-surgical treatment options, including endoscopic intervention and cell therapy. Objectively reviewing natural and artificial sweeteners and critically examining issues such as public health initiatives, government mandated taxes for unhealthy foods and environmental planning, no stone is left unturned in gathering the latest practical information. As such, the book will appeal to seasoned specialists, as well as students and healthcare professionals in training.

Contents:

Foreword

Block I: Epidemiology, inheritance, environment, and pathways

Introduction - Joel Faintuch j.faintuch @ hc.fm.usp.br Hospital das Clinicas, Sao Paulo University Medical School Sao Paulo, Brazil
Sonia Pou - Nutrition transition and obesity burden in Argentina pousonia @ hotmail.com Scientific and Technologic Center CONICET, Cordoba, Argentina
Alexei Volaco -Social and economic status: the link between obesity and diabetes avolaco @ yahoo.com.br PontificialCatholic University, Curitiba, PR, Brazil
Jean Claude Mbanya- Cost of diabetes in Africa jcmbanya @ yahoo.co.uk Faculty of Medicine and Biological Science, University of Yaounde, Cameroon
Marta Viana- White and brown adipose tissue mviana @ ceu.es School of Pharmacy, University CEU San Pablo, Madrid, Spain
Brooks Leitner - Leveraging brown adipose tissue for metabolic therapy brooks.leitner @ yale.eduSchool of Medicine, Yale University, New Haven, CT, USA
Antonello Lorenzini- Obesity and aging Antonello.lorenzini @ unibo.it School of Pharmacy, University of Bologna, Italy
Giuseppe . Iacomino - Micro RNAs in obesity and metabolic diseases Giuseppe . Iacomino @ isa.cnr.it Institute of Food Sciences, Rome, Italy
Nikhil.Dhurandar - From adipogenic adenoviruses to anti-diabetic drug Nikhil.Dhurandar @ ttu.edu Department of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA
Ana Carolina Proenca da Fonseca - Genetics and obesity Ana.proenca @ ioc.fiocruz.br Oswaldo Cruz Institute, Rio de Janeiro,RJ, Brazil
Peter Congdon - Urban environment and obesity P.congdon @ qmul.ac.uk School of Geography, Queen Mary University of London, London, UK
Umesh Yadav - Adipose tissue inflammation umeshyadav @ cug.ac.in School of Life Sciences, Central University of Gujarat, Gandhinagar, India
Umesh Yadav- Cross talk between adipocytes, macrophages, and other imune cells umeshyadav @ cug.ac.in School of Life Sciences, Central University of Gujarat, Gandhinagar, India
Alexandre Assuane- Diabetes in figures Alexandre Assuane @ hotmail.com Medical Faculty of the FriedrichWilhelms University, Bonn, Germany
Carlos Mandarim - Pancreatic islets: cell biology and therapy for diabetes mandarim @ uerj.br Faculty of Medicine, State University of Rio de Janeiro, Rio de Janeiro, Brazil
Mahaneem Mohamed - Advanced glycation end products in obesity and comorbidities mahaneem @ usm.my School of Medical Sciences, University Sains Malaysia, Penang, Malaysia
Kalliopi Kotsa - The anti-incretin theory kalmanthou @ yahoo.gr MedicalSchool, AristotleUniversity, Thessaloniki, Greece

Block II: Genomics,metabolomics and other omics
David Meyre - Personalized treatment of Mendelian forms of obesity meyred @ mcmaster.ca McMaster University School of Medicine, Hamilton, ON, Canada
Marcus Pezzolesi - Genetic basis of diabetic kidney disease Marcus.pezzolesi @ hsc.utah.edu University of Utah School of Medicine, Salt Lake City, UT, USA
Meenu Ghai - Epigenetics and early detection of diabetes Meenu Ghai Ghai @ ukzn.ac.za School of Life Sciences, University of Kwazulu- Natal, Durban, South Africa
Jacopo Troisi - Salivary and urinary metabolome in pediatric obesity and metabolic syndrome troisi @ theoreosri.com CEO, Theoreo SRL, Salerno, Italy
Suchart Kothan - Metabolome in obesity suchart.kothan @ cmu.ac.th Chiang Mai University Faculty of Associated Medical Science, Chiang Mai, Thailand
Benita Percival - Metabolomics in diabetes benita.c.percival @ dmu.ac.uk Faculty of Health and Life Sciences, De Montfort University, Leicester, UK
Hemant_Kulkarni - Lipidomics in type 2 diabetes kulkarnius @ yahoo.com, M & H Research, San Antonio, TX, USA
Francisco Javier Ruiz Ojeda - Effects of sweeteners on gut microbiota FJRojeda @ gmail.com Institute for Diabetes and Obesity, Helmholtz Zentrum Munchen, Germany
Prabhanshu Tripathi - The microbiome in type 2 diabetes prabhanshu @ thsti.res.in Translational Health Science and Technology Institute, Faridabad, India
Tatsuhiko Azegami- Immunotherapeutic approach to obesity t.azegami-1114 @ z2.keio.jp Keio University School of Medicine, Yokohama, Kanagawa, Japan

Block III: Associated disorders and obesity paradoxes
Uzma Zargham - Metabolic syndrome Uzma.Zargham @ gmail.com Lahore Medical and Dental College, Lahore, Pakistan
Pawel Matusik - Metabolic syndrome diagnosis in children pmatusik73 @ gmail.com Medical University of Silesia, Katowice, Poland
Yusuf Yilmaz - Non alcoholic fatty liver disease drYusufYilmaz @ gmail.com Marmara University School of Medicine, Istanbul, Turkey
Veisel Tahan - Non alcoholic fatty pancreas disease tahanv @ health.missouri.edu School of Medicine, University of Missouri, Columbia, MO, USA
Nitin Kapoor - Normal weight obesity nitin.kapoor @ cmcvellore.ac.in ChristianMedical College, Vellore, India
Phil Chilibeck- Polycystic ovary and sarcopenic obesity phil.chilibeck @ usask.ca College of Kinesiology, University of Saskatchewan, Saskatoon, SK, Canada
Jennifer Panganiban - Pediatric obesity panganibaj @ email.chop.edu Children`s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA
Erika di Zazzo - Links between obesity and cancer erika.dizazzo @ unimol.it Faculty of Medicine, University of Molise, Campobasso, Italy
Paula Moreira - Obesity, diabetes, and cognitive impairment venta @ ci.uc.pt Faculty of Medicine, University of Coimbra, Coimbra, Portugal
Antonio Teixeira - Pathways linking obesity to neuropsychiatric disorders Antonio.l.teixeira @ uth.tmc.edu Faculty of Medicine, University of Texas Health Science Center, Houston, TX, USA
Vijay Kumar Chattu - Sleep and obesity vijay.chattu @ mail.utoronto.ca Department of Psychiatry, Faculty of Medicine, University of Toronto, Ontario, Canada
Marijana Tadic- Heart failure and the obesity paradox marijana_tadic @ hotmail.com School of Medicine, University of Belgrade, Belgrade, Serbia
Samanta Rahul - Cardiomyopathy and obesity paradox rahuldocuk @ yahoo.co.uk Department of Cardiology, The Canberra Hospital, Canberra, Australia
Christopher Kellner- Obesity paradox: intracerebral hemorrhage Christopher.kellner @ gmail.com Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Radica Alicic - Inflammatory mechanisms and diabetic kidney disease radica.alicic @ providence.org University of Washington School of Medicine, Spokane, WA, USA
Finn Diderichsen - Diabetes and depression in Brazil fidi @ sund.ku.dk University of Copenhagen School of Medicine, Copenhagen, Denmark
Dong Li - Contribution of hyperglycemia and unhealthy diet to cardiovascular mortality dong.li2 @ emory.edu School of Medicine, Emory University, Atlanta, GA, USA
Samuel Seidu- Gestational diabetes sis11 @ le.ac.uk College of Life Sciences, University of Leicester, UK
Megan Jones - Advances in gestational diabetes mjobgyn @ gmail.com HighRisk PregnancyCenter, Las Vegas, NV, USA
Chih Hao Chen Ku - Vascular complications of diabetes chenku2409 @ gmail.com Clinica Los Yoses, San Jose, Costa Rica



Block IV: General therapy and prevention
Clipper Young - What we know and what we dont about non nutritive sweeteners Clipper.young @ tu.edu Touro University California College of Osteopathic Medicine, Vallejo, CA, USA
Shilpa Tejpal - Personalized molecular feedback for weight loss tejpalshilpa @ gmail.com University of Warwick School of Medicine, Coventry, UK
Suzanne Cuda - Pediatric obesity algorithm Suzanne.cuda @ bcm.edu Baylor College of Medicine, San Antonio, TX, USA
Antonello Nicolini - Therapeutic options in obesity hypoventilation syndrome Antonellonicolini @ gmail.com Ospedale di Sestri Levante, Genova, Italy
Sarah.Cuschieri - Type 2 diabetes: an unresolved disease Sarah.Cuschieri @ um.edu.mt University of Malta School of Medicine, Valletta, Malta
Greet Van den Berghe - Glucose control in the ICU greet.vandenberghe @ kukeuven.be University of Leuven School of Medicine, Leuven, Belgium

Block V: Innovative endoscopic , cell therapy, and other interventions
Vitor Brunaldi - Endoscopic interventions School of Medicine, University of Sao Paulo, Ribeirao Preto, SP, Brazil
Clifford Weiss - Arterial embolization cweiss @ jhmi.edu Johns Hopkins School of Medicine, Baltimore, MD, USA
Niranchan Paskaranandavadivel Gastric pacing in gastroparesis Npas004 @ aucklanduni.ac.nz Auckland Bioengineering Institute, University of Auckland, New Zealand
Bluma L Faintuch - Pancreatic beta cell imaging blfaintuch @ Hotmail.com Institute Of energetic and Nuclear Research IPEN/CNEN, Sao Paulo, SP, Brazil
Monica Finessi - Cancer staging with 18F FDG PET/CT in hyperglycemic patients monica.finessi @ unito.it Doctoral School in Life and Health Sciences, University of Torino, Torino, Italy
Jonathan Lakey - Stem cells for diabetes jrtlakey @ gmail.com University of California School of Medicine, Irvine, CA, USA
Mahua Choudhury- Promises of nanotherapeutics in diabetes drmc @ tamu.edu Graduate Faculty Nutrition and Food Science, Texas A & M University, College Station, TX, USA

Block VI: Pharmacological therapy and cost containment
Gopal Khatic - Pharmacotherapy of diabetes gopal_niper @ rediffmail.com School of Pharmaceutical Sciences, Lovely ProfessionalUniversity, Phagwara, Punjab, India
Andrei Sposito - GLP-1 analogs for diabetes andreisposito @ gmail.com Faculty of Medical Sciences, State University of Campinas, Campinas, SP, Brazil
Lorena Alarcon-Casas Wright - Insulin and Type 1 diabetes lorenaac @ uw.edu University of Washington School of Medicine , Seattle, WA, USA
Esma Isenovic -Drug delivery systems for diabetes treatment isenovic @ yahoo.com Institute Vinca, University of Belgrade, Serbia
Michael Chan - Treatment of diabetes and heart failure chanmcy @ gmail.com School of Medicine, University of Alberta, Calgary, Alberta, Canada
Ravi Kant - Cardiovascular impact of newer diabetes medications kant.ravi.md @ gmail.com Medical University of South Carolina, Charleston, SC, USA
Deependra Singh - Pathogenesis, molecular targets, and treatment of diabetic woundsDeependraiop @ gmail.com Institute of Pharmacy, RaviShankarShukla University, Raipur, India
Zoltan Taybani- Simplifying complex insulin regimens taybanizoltan @ gmail.com Bekes CountyCentral Hospital, Bekescsaba, Hungary
Ramon Sanguino Galvan Economic benefits of diabetes day hospital sanguino @ unex.es School of Economics, University of Extremadura, Badajoz, Spain



Block VII: Bariatric and metabolic surgery
Jaime Ruiz-Tovar Polo - Bariatric and metabolic operations jruiztovar @ gmail.com School of Medicine, University Rey Juan Carlos, Madrid , Spain
Faidon Magkos -One anastomosis gastric bypass in the treatment of obesity fma @ nexs.ku.dk University of Copenhagen School of Science, Copenhagen, Denmark
Candice Silverman - Robotic bariatric surgery drcsilverman @ gmail.com JohnFlynn Hospital, Gold Coast, Queensland, Australia
Shanu Kothari - Role of obesity and bariatric surgery in knee and hip osteoarthritis snkothar @ gundersenhealth.org Gundersen Health System, LaCrosse Campus, Lacrosse, WI, USA
Ricardo Cohen - Metabolic deterioration and revisional bariatric and metabolic surgery Ricardo.cohen @ haoc.com.br Hospital Oswaldo Cruz, Sao Paulo, SP, Brazil
Capecomorin Pitchumoni -Malnutrition in obesity before and after bariatric surgery pitchumoni @ hotmail.com Saint Peters University Hospital, Somerset, NJ, USA

Block VIII: Apps, drugs , artificial intelligence, and public health interventions
Fabrizio Ferretti - Beverage and energy dense food taxation fabrizio.ferretti @ unimore.it Department of Communication and Economy, University of Modena, Reggio Emilia, Italy
Lynnette Nathalie Lyzwinski - Mobile health interventions for obesity lynnettenathalie @ icloud.com Department of Public health and Primary Care, Strangeways Research Laboratory, Cambridge University, Cambridge, UK
Ioannis Kavakiotis - Machine learning and data mining in obesity ikavakiotis @ gmail.com Hellenic Pasteur Institute, Athens, Greece
Thomas Marshall - Machine learning and obesity prevention in adolescents thomasemarshall @ gmail.com Business Department, Auburn University, Auburn, AL, USA
Arthur Bertachi - Machine learning in type 1 diabetes abertachi @ utfpr.edu.br School of Engineering, Federal Technologic University of Parana, Ponta grossa, PR, Brazil
Aleksey Velikorodny - Machine learning in diabetes complications asvelikorodny @ gmail.com Department of Genetics, Citology and Bioengineering, Voronezh State University, Russian Federation
Maushmi Kumar - Drug pipeline for obesity therapy maushmiskumar @ gmail.com Shobhaben Pratapbhal Patel School of Pharmacy and Technology Management, Mumbai, India
Juliana Goncalves - Melanocortin 4 receptor agonists in obesity juliana.goncalves @ tum.de Institute of Pathology, Technical University Munich, Germany



Block IX: Obesity devices and supplemental material
Joel Faintuch - Medical devices for obesity management j.faintuch @ hc.fm.usp.br Hospital das Clinicas, Sao Paulo University Medical School Sao Paulo, Brazil
Joel Faintuch - Glossary j.faintuch @ hc.fm.usp.br Hospital das Clinicas, Sao Paulo University Medical School Sao Paulo, Brazil
Joel Faintuch - Useful internet sites j.faintuch @ hc.fm.usp.br Hospital das Clinicas, Sao Paulo University Medical School Sao Paulo, Brazil