Main description:

This two-volume text reviews the field and pinpoints the types of organometallics which are most promising for further exploration. Although no organometallic compound is currently in therapeutic use, the success of Cisplatin and related platinum complexes shows the promise that some organometallics may have equal or superior therapeutic value. Many have already been tested as cancerostatics, and some have exhibited remarkable activity. Thus, new paths of exploration have been opened in this field, and it is important at this stage to analyze these results and evaluate the prospects. The book is intended as a communication link between the synthetic chemist and the physician involved in testing and therapy. It also provides a better and more beneficial understanding of organometallics for the nonchemist involved in the long process from the chemist's bench to the clinician's syringe.

Contents:

VOLUME I: MAIN GROUP METAL COMPOUNDS 1. Organometallics in Cancer Chemotherapy 2. Organoboron Compounds 3. Organosilicon Compounds 4. Organoger-manium Compounds 5. Organotin Compounds 6. Organolead Compounds 7. Organoarsenic Compounds 8. Organoantimony Compounds 9. Organotellurium Compounds