Main description:

The field of rheumatology has undergone numerous exciting advances in recent years, especially the development of biological drugs with novel targets, made possible by rapid advances in the basic science of musculoskeletal diseases together with improved imaging techniques. This thoroughly revised fourth edition of the Oxford Textbook of Rheumatology reflects the changing face of the specialty and the many recent advances in the science, treatment, and understanding
of rheumatic diseases.

The focus of this comprehensive reference work is the presentation and management of rheumatic conditions at all ages. Where relevant, treatment approaches are evidence-based and cross-referenced to national and international guidelines. Each clinical chapter provides up-to-date treatment advice illustrated with clinical vignettes as appropriate, and the authors consistently emphasize the overlap of rheumatology with other disciplines. With full colour illustrations throughout and a
complementary online version, the Oxford Textbook of Rheumatology, Fourth Edition is an essential reference for all trainees and specialists in the field.

Contents:

Section 1 Clinical presentations of rheumatic disease in different age groups
1: Lori Tucker: The child patient
2: Janet E. McDonagh: Young people and transitional care in rheumatology
3: Paul Thompson: The adult patient
4: Fraser Birrell: The elderly patient
5: Helen Foster: Principles of clinical examination in children
6: Lesley Kay: Principles of clinical examination in adults
Section 2 Common clinical problems of rheumatic disease
7: Marc Lillicrap: Monoarticular disease
8: Andrew Keat: Oligoarticular disease
9: Ade Adebajo: Polyarticular disease
10: Raashid Luqmani: The systemically ill patient
11: Karl Gaffney: Spinal pain
12: Candy McCabe & Helen Cohen: Pain and Fatigue
13: Yuki Kimura: The limping child
14: Athimalaipet Ramanan: The systemically unwell child
15: Elspeth Wise: Primary care presentation
Section 3 Clinical presentations: Views from different perspectives
16: Monika Oestensen: Obstetrics and pregnancy
17: Christopher Griffiths: The skin
18: Andrew Graham & Clare Galton: The nervous system
19: Gerry Coghlan: The cardiovascular system
20: The respiratory system
21: Gerhard Rogler: The gastrointestinal system
22: Rainer Straub: The neuroendocrine system
23: Clive Kelly: Malignancy
24: Miles Stanford: The eye
25: Mark Little: The kidney
26: Stanton Newman: Psychology
Section 4 The impact of rheumatic disease
27: Deborah Symmons: Epidemiology of rheumatic diseases
28: Piet van Riel: Assessment of rheumatic disease
29: David L. Scott: Outcomes
30: Vibeke Strand: Design of clinical trials in rheumatology
31: Sonja Merkesdal & Wilfried Mau: Health economics
32: Tuulikki Sokka: Co-morbidities of rheumatic disease
33: Ross Wilkie: Social aspects (work)
34: David Isenberg & Angela Zink: Biologics registries
35: Kirsten Minden: Outcomes of paediatric rheumatic disease
36: Ciaran Duffy: Assessment of paediatric rheumatic disease
Section 5 Genetics and environment
37: Anne Barton: Basics of genetics
38: Cyrus Cooper: Environment
39: Steffen Gay and Michel Neidhart: Epigenetics
40: Sebastien Viatte: Genetics of rheumatoid arthritis
41: Matthew Brown: Genetics of Spondyloarthropathies
42: Tim Vyse: Genetics of Connective tissue diseases
43: Wendy Thomson & Anne Hinks: Genetics of juvenile rheumatic disease
44: Alexander Macgregor: Genetics of osteoarthritis
45: John McBeth: Genetics of chronic musculoskeletal pain
Section 6 Tissue in health and disease
46: Mike Benjamin: The normal functional anatomy of joints
47: Lindsey Hooper: Measuring movement and gait
48: Reinhard Voll: Innate vs. acquired immunity
49: Pierre Miossec: T Cellular side of acquired immunity (T cells)
50: Thomas Doerner: Cellular side of acquired immunity (B cells)
51: Chris Buckley: Fibroblasts and mesenchymal cells
52: Costantino Pitzalis: Synovial pathology
53: Georg Schett: Bone turnover
54: Martin Rudwaleit: Enthesitis
55: Robert Dinser: Skeletal muscle physiology and damage
56: Thomas Pap: Joint biochemistry
57: Justin Mason: Vascular biology
58: Elena Neumann: Acute phase responses and adipocytokines
59: Rainer Straub & Hans-George Schaible: Pain neurophysiology
60: Lucy Wedderburn: The pathogenesis of juvenile idiopathic arthritis
Section 7 Practical investigation of rheumatic disease
61: Patrick Kesteven: Haematology
62: Patrick Twomey: Biochemical investigation of rheumatic diseases
63: Neil McHugh: Auto-immune serology
64: Matthew Pickering: Complement
65: Mike Benjamin: Limb anatomy and medical imaging
66: Andrew Grainger: Radiographic imaging
67: Phil Platt: Ultrasound
68: Phil O'Connor: Magnetic resonance imaging
69: Geoff Hide: Computed tomography
70: Adil Al-Nahhas: Nuclear medicine
71: Karl Johnson: Imaging in children
72: Tony Freemont: Assessment of synovial joint fluid
73: Benjamin Schreiber: Cardiopulmonary investigation
74: Julian Blake: Electrophysiology
Section 8 Management of rheumatic disease
75: David Walker: Patient education
76: Sarah Ryan: Multidisciplinary treatment
77: Kay Brune: Cyclooxygenase inhibitors
78: Philip Conaghan: Analgesics
79: Frank Buttgereit: Glucocorticoids
80: Joanna Ledingham: Immunosuppressants
81: Roy Fleischmann: Signalling pathway inhibitors
82: Andrew OEstoer: Anti-cytokine biologics
83: John Isaacs: Cellular therapies
84: Daniel Lovell: Biologics in paediatric rheumatic diseases
85: Alan Tyndall: Stem cell therapies
86: Andrew McCaskie: Tissue engineering
87: Phil Platt: Injection therapy
88: Dorothy Pattison: Diet and obesity
89: Edzard Ernst: Alternative therapies
90: Ian McNab: Principles of upper limb surgery
91: Damien Griffin: Principles of lower limb surgery
92: Jeremy Fairbank: Principles of spine surgery
93: Loreto Carmona: Perioperative management of immunosuppression
94: Van Assen: Vaccination in immunocompromised adults
95: Nico Wulffraat: Vaccination in immunocompromised children
96: Ravelli & Ruperto: Principles of management of juvenile idiopathic arthritis
97: Tarnya Marshall: Anti-rheumatic drugs in pregnancy and lactation
Section 9 Infection in rheumatic disease
98: Max Field: Septic arthritis in adults
99: Julia Clark: Bone and joint infections in children
100: Jeremy Field: Osteomyelitis
101: Andreas Krause: Lyme disease
102: Stanley J. Naides: Viral arthritis
103: Rita Abdulkader: Mycobacterial diseases
104: Eliseo Pascual: Brucellar arthritis
105: Yusuf Patel: Parasitic involvement
106: Richard Watts: Fungal arthritis
107: Susan Hopkins: Opportunistic infection
108: Andrew C. Steer: Rheumatic fever
Section 10 Rheumatoid arthritis
109: Andy Cope: Pathogenesis of rheumatoid arthritis
110: Daniel Aletaha: Rheumatoid arthritis - diagnosis
111: Gerd Burmester: Rheumatoid arthritis - clinical features
112: Chris Deighton: Rheumatoid arthritis - management
Section 11 Spondyloarthropathies
113: Joachim Sieper: Axial Spondyloarthritis
114: Philip Helliwell: Psoriatic arthritis
115: J.S. Hill Gaston: Reactive arthritis and enteropathic arthropathy
Section 12 Arthropathies primarily occuring in childhood
116: Eileen Baildam: Juvenile idiopathic arthritis
Section 13 Systemic lupus erythematosus
117: Caroline Gordon: Systemic lupus erythematosus - clinical features and aetiopathogenesis
118: David Isenberg: Systemic lupus erythematosus - management
119: Michael Beresford: Paediatric onset systemic lupus erythematosus
120: Munther A. Khamashta: The antiphospholipid antibody syndrome
Section 14 Scleroderma
121: Chris Denton: Systemic sclerosis
122: Francesco Zulian: Paediatric scleroderma and related disorders
123: Cate Orteu: Nephrogenic systemic fibrosis
Section 15 Myositis
124: Hector Chinoy: Polymyositis and dermatomyositis in adults
125: Clarissa Pilkington: Paediatric polymyositis and dermatomyositis
126: Mark Roberts: Non-inflammatory myopathies
Section 16 Sjoegren's syndrome
127: Simon Bowman: Sjoegren's syndrome: clinical features
128: Wan-fai Ng: Sjoegren's syndrome: management
Section 17 Overlap/undifferentiated syndrome
129: Ariane Herrick: Overlap/undifferentiated syndrome
Section 18 Vasculitis
130: Richard A.Watts: Classification and diagnosis
131: Julia Holle: Clinical features of primary ANCA-associated vasculitis
132: David Jayne: Treatment of ANCA vasculitis
133: Carlo Salvarani: Large vessel vasculitis
134: Charles Raine: Polymyalgia rheumatica
135: Hasan Yazici: Behcet's syndrome
136: Paul Brogan: Paediatric vasculitis
137: Richard A. Watts: Miscellaneous vasculitides
Section 19 Osteoarthritis
138: Tonia Vincent: Pathogenesis of osteoarthritis
139: Mike Doherty: Clinical features of osteoarthritis
140: Phil Conaghan: Osteoarthritis management
Section 20 Crystal arthropathies
141: Nicola Dalbeth: Gout
142: Ed Roddy: Calcium pyrophosphate crystal deposition (CPPD)
Section 21 Diseases of bone and cartilage
143: David Reid: Osteoporosis
144: Stuart Ralston: Paget's disease of bone
145: Nick Bishop: Paediatric metabolic bone disease
146: Ashok Bhalla: Disorders of bone mineralisation: Osteomalacia
147: Craig Gerrand: Bone Tumours
148: Stefan Rehart: Avascular necrosis
149: Thomas Bardin: Renal osteodystrophy
150: Paul Wordsworth: Skeletal dysplasias
Section 22 Regional rheumatic disease
151: Andrew Ostor: Shoulder
152: Karen Walker-Bone: Elbow
153: Karen Walker-Bone: Forearm, hand and wrist
154: Cathy Speed: Pelvis, groin and thigh
155: Roger Wolman: Knee
156: Tony Redmond: Foot and ankle
157: David Walsh: Cervical and lumbar spine
158: Kristin Houghton: Childhood regional conditions
159: Alan Hakim: Hypermobility syndromes
160: Nick Shenker: Fibromyalgia and chronic widespread pain syndromes: adult onset
161: Jacqui Clinch: Fibromyalgia and chronic widespread pain syndromes: adult onset
162: Nicola Maffulli: Sports and exercise injuries
Section 23 Miscellaneous conditions
163: Phil Hawkins: Amyloidosis
164: Helen Lachmann: Auto-inflammatory diseases
165: Cord Sunderkotter: Panniculitides
166: Thomas Krieg: Neutrophilic dermatoses
167: Joachim Mueller-Quernheim: Sarcoidosis
168: Alexei Grom: Macrophage activation syndrome
169: Hermann Einsele: Multicentric reticulohistiocytosis
170: Bernard Manger: Inherited metabolic diseases
171: Gerry Rayman: The rheumatological manifestations of endocrine disorders
172: David Rees: Haemoglobinopathies
173: Graeme Carroll: Haemochromatosis