Main description:

Pediatric Epilepsy Surgery Techniques: Controversies and Evidence provides a roadmap for clinicians in addressing difficult decision-making by succinctly summarizing the evidence for surgical treatments in pediatric drug-resistant epilepsy. With the field of pediatric epilepsy surgery having expanded significantly over the last 10 years, combined with high variability in practice and several emerging technologies with expanding evidence, this volume addresses several dichotomies in decision-making, both in terms of surgical modalities as well as surgical techniques. Chapters compare DBS, VNS/RNS, resection and other modalities, as well as surgical methods, including vertical vs. lateral hemispherectomy, robotic-guided surgery, and laser vs. resection.

With recent approval and application of several medical advances in epilepsy surgery over the last five years, this book provides readers the scientific literature and daily practice content they need for an evidence-based approach for surgical care.

Contents:

1. Evidence in Pediatric Epilepsy Surgery
2. Ethical considerations in contemporary Pediatric Epilepsy Surgery
3. Controversies in timing of pediatric epilepsy surgery - is earlier better?

Invasive Investigation
4. Electrocorticographic evaluation of epileptogenicity - Traditional vs novel biomarkers to guide surgery
5. Invasive Monitoring - stereoelectroencephalography (SEEG) vs. subdural electrode (SDE) evaluation vs hybrid evaluation

Resective or ablative surgery
6. Intra-operative adjuncts to optimize the surgical treatment of drug-resistant epilepsy - Do new tools improve outcome?
7. medial Temporal lobe Epilepsy (TLE) - selective amygdalohippocampectomy (SAH) vs. anterior temporal lobectomy (ATL)
8. Epilepsy in eloquent cortex- Resection vs. responsive neurostimulation (RNS)
9. Lesional Epilepsy - Lesionectomy vs. ECoG-guided resection
10. Insular/peri-Sylvian Epilepsy - Resection vs. Stereotactic ablation (MR-guided laser ablation/Radiofrequency ablation)
11. Hypothalamic Hamartoma - Stereotactic radiosurgery (SRS) v. Stereotactic ablation (MR-guided laser ablation/Radiofrequency ablation) v. MRFUS
12. Tuberous Sclerosis Complex - Lesionectomy vs lesionectomy plus

Disconnective Procedures
13. Functional hemispherotomy - Vertical vs. Lateral approach
14. Minimally Invasive Hemispherotomy - Endoscopic Assisted vs. Radiofrequency Disconnection
15. Lobar/Multi-lobar epilepsy - Resection vs. Disconnection
16. Lennox-Gastaut Syndrome - Callosotomy vs. Vagal nerve stimulation (VNS)
17. Corpus Callosotomy - Ant 2/3rd (2-stage) v. Complete (1-stage)

Neuromodulation
18. TLE with preserved function: Multiple hippocampal transection (MHT) vs. Neuromodulation (DBS, RNS)
19. Neuromodulation - Neuromodulation vs 'resective', VNS vs. DBS (TSC, LGS, etc)