Main description:

The presentation of kidney diseases can vary widely between children and adults as can age-related differential diagnoses and the consequences of treatment. This comprehensive and practical guide to pediatric nephropathology covers a range of conditions and diseases, including abnormal kidney development, glomerular diseases, vascular diseases and transplant pathology. Special emphasis is placed on integrating mechanisms of disease to pathology and therapeutic options. The book also includes ancillary testing such as genetics, as these are fast becoming the gold standard for a number of paediatric kidney diseases. Over a hundred high-quality colour images are included, fully annotated to display the key features of the diseases discussed. Summaries of key points and knowledge gaps condense vital information for an accessible read by busy clinicians and trainees. An online version of the book with expandable figures can be accessed on Cambridge Core, via the code printed on the inside of the cover.

Contents:

Introduction Helen Liapis; Part I. Normal Kidney Development: 1. Normal human kidney development and congenital anomalies of the kidneys and urinary tract (CAKUT) Paul Winyard, Raffaele Napolitano and Neil J. Sebire; 2. Distribution of pediatric renal biopsy diagnoses in a large single center and rare pediatric cases Alejandro Best Rocha; 3. Low nephron mass in premature babies Paul Winyard; Part II. Glomerular Diseases: 4. Idiopathic and hereditary proteinuric glomerular diseases Danica Galesic Ljubanovic and Parker Wilson; 5. Haematuric glomerular diseases (Collagenopathies) Catherine Horsfield and Helen Liapis; 6. Immune complex mediated glomerular diseases Pablo Xavier Cannata; 7. Pathology of inherited metabolic diseases affecting the kidney Sabine Leh and Surya V. Seshan; 8. Glomerular diseases with fibrillary deposits Nattawat Klomjit, Ladan Zand and Mariam Priya Alexander; 9. Mitochondrial diseases in the pediatric kidney Alessia Buglioni and Mariam Priya Alexander; Part III. Tubulointerstitial Diseases: 10. Hereditary and acquired tubulointerstitial diseases Amelie Dendooven and Elena Levtchenko; 11. Tubulointerstitial diseases with crystal and pigment deposits Tri Nguyen and Joris Roelofs; Part IV. Vascular Diseases: 12. Vascular diseases Thorsten Wiech, Silke Brix and Peter F. Zipfel; Part V. Infectious Diseases: 13. Infectious diseases Marjan Afrouzian and Stanley de Almeida Araujo; Part VI. Cystic Diseases: 14. Cystic diseases: autosomal dominant polycystic kidney disease, Autosomal recessive polycystic kidney disease Carrie Phillips, Bharathi V. Reddy and Stephen M. Bonsib; 15. Tuberous sclerosis complex Christie Boils; 16. Glomerulocystic diseases Pablo Cannata; 17. Nephronopthisis complex (NPH- ADTKD) Kerstin Amann; Part VII. Solid Tumors of the Kidney and Bladder: 18. Solid tumors of the kidney and bladder Maureen O'Sullivan and John O'Neill; Part VIII. Distribution of Pediatric Renal Biopsy Diagnoses in a Large Single Center and Rare Pediatric Cases: 19. Transplant pathology Agnieszka Perkowska-Ptasinska.