Main description:

This monograph provides a comprehensive review of the poxvirus family with a particular emphasis on current developments. It includes the latest insights into poxviral molecular biology, diagnosis, therapy, vaccine development and the beneficial exploitation of these viruses in biomedical research. Each chapter is written by a leader in the field, and the book includes historical perspectives and summaries of recent advances in the field.

Contents:

Historic aspects and early smallpox management approaches in the new world.- Genus Orthopoxvirus: Vaccinia virus.- Genus Orthopoxvirus: Variola virus.- Genus Orthopoxvirus: Monkeypox virus.- Genus Orthopoxvirus: Cowpox virus.- Genus Molluscipoxvirus.- Genus Yatapoxvirus.- Genus Parapoxvirus.- Genus Capripoxvirus.- Genus Leporipoxvirus.- Genus Suipoxvirus.- Genus Avipoxvirus.- Subfamily Entomopoxvirinae.- Vaccines and vaccination.- Poxvirus diagnostics.- Therapy of poxvirus infections.- Environmental resistance, disinfection, and sterilization of poxviruses.- Early disease management strategies in case of a smallpox outbreak.- Recombinant poxviruses in biomedical research.- Immunomodulation by poxviruses.- Immunomodulation by inactivated Parapoxvirus ovis (PPVO) - therapeutic potential