Main description:

This comprehensive volume provides a platform from which both major and minor infectious diseases related issues are addressed in-depth among this highly susceptible population. The book begins with an overview of infections in various modalities. This is followed by chapters on clinical disorders, etiologic agents, therapeutics, and infection prevention. Chapters include easy-to-follow figures and tables, radiologic images, and pictorial demonstrations of various disease states to familiarize and reacquaint the transplant clinicians and surgeons in practice and training, and those belonging to subspecialties providing supportive care for these patients. Discussions to enumerate the noninfectious causes that mimic infectious diseases; clinical relevance and effective utility of existing and emerging diagnostic tools are presented throughout the book. Authored by leaders in their fields, this book is the go-to reference for management of patients undergoing hematopoietic and solid organ transplantation.

Contents:

Chapter 1

Infections in Transplantation: Introduction and Overview

Amar Safdar

Chapter 2

Infections in Heart, Lung, and Heart-Lung Transplantation

Andres F. Henao-Martinez and Jose G. Montoya

Chapter 3

Infections in Liver Transplantation

B. Sharmila Mohanraj, Amol S. Rangnekar, and Joseph G. Timpone, Jr

Chapter 4

Infections in Kidney and Pancreas Transplantation

Megan K. Morales, Matthew Cooper, Peter Abrams, and Joseph G. Timpone, Jr

Chapter 5

Infections in Intestinal and Multivisceral Transplantation

Raffaele Girlanda, Joseph G. Timpone, Jr, Kevin M. Soriano, and Thomas M. Fishbein

Chapter 6

Infections in Limbs, Integuments, and Face Transplantation

Justin M. Broyles and Chad R. Gordon

Chapter 7

Principles of Hematopoietic Stem Cell Transplantation

Michelle Limei Poon, Richard E. Champlin, and Partow Kebriaei

Chapter 8

Infections in Pediatric Transplant Recipients

Aspasia Katragkou, Lucy O'Connor, Emmanuel Roilides, and Thomas J. Walsh

Chapter 9

Febrile Neutropenia in Transplant Recipients

Lior Nesher and Kenneth V. I. Rolston

Chapter 10

Cytopenias in Transplant Patients

Maura Barry, Sunandana Chandra, and Kenneth B. Hymes

Chapter 11

Infections in Allogeneic Stem Cell Transplantation

Marcus R. Pereira, Stephanie M. Pouch, and Brian Scully

Chapter 12

Complications Arising from Preparatory Conditioning Regimens for Stem Cell Transplantation

Jasmine Zain and Merav Bar

Chapter 13

Intravascular Catheter and Implantable Device Infections in Transplant Patients

Nasia Safdar, Cybele Lara R. Abad, and Dennis G. Maki

Chapter 14

Surgical Site Infections: Wound and Stump Infections

Nasia Safdar, Sara A. M. Zerbel, and Elizabeth Ann Misch

Chapter 15

Endovascular Infections and Endocarditis

Walter Zingg and Didier Pittet

Chapter 16

Gastrointestinal Infections and Clostridium difficile Infection

Stephen Harold and Herbert L. DuPont

Chapter 17

Hepatobiliary Tract Infections

Jonathan Merola, Robert M. Mocharla, Alexander Z. Jow, Samuel H. Sigal, and Amar Safdar

Chapter 18

Ocular Infections in Transplant Patients

Ann-Marie Lobo, Lucia Sobrin, and Marlene L. Durand

Chapter 19

Intracranial, Spinal, and Paraspinal Infections in the Transplant Recipient

Matthew W. McCarthy, Axel Rosengart and Thomas J. Walsh

Chapter 20

Respiratory Tract Infections: Sinusitis, Bronchitis, and Pneumonia

Benjamin A. Miko, Marcus R. Pereira, and Amar Safdar

Chapter 21

Respiratory Tract Diseases That May Be Mistaken For Infection

Robert M. Kotloff, Burton F. Dickey, and Nicholas Vander Els

Chapter 22

Skin and Soft Tissue Infection in Transplant Recipients

Robert G. Micheletti and Carrie L. Kovarik

Chapter 23

Cutaneous Lesions that Mimic Infection in Transplant Patients

Ana Ciurea and Sharon Hymes

Chapter 24

Staphylococcus, Streptococcus, and Enterococcus

Amar Safdar and Donald Armstrong

Chapter 25

Enterobacteriaceae in Transplantation

Kathryn Whitaker, Valerie Cluzet, and Emily A. Blumberg

Chapter 26

Pseudomonas, Stenotrophomonas, Acinetobacter, and Other Non-Fermentative Gram-Negative Bacteria & Medically Important Anaerobic Bacteria in Transplant Recipients

Kenneth V.I. Rolston and Amar Safdar

Chapter 27

Nocardiosis and Actinomycosis

Heather E. Clauss and Bennett Lorber

Chapter 28

Listeriosis

Heather E. Clauss and Bennett Lorber

Chapter 29

Tuberculosis

Cynthia Portal-Celhay and Jennifer A. Philips

Chapter 30

Nontuberculous Mycobacterial Disease in Transplant Recipients

Julie V. Philley, Amar Safdar, and Charles L. Daley

Chapter 31

Invasive Fungal Disease in the Transplant Population: An Overview

Jennifer L. Saullo, John R. Perfect, and Barbara D. Alexander

Chapter 32

Candida Infections in Hematopoietic and Solid Organ Transplant Recipients

Alison G. Freifeld and Carol A. Kauffman

Chapter 33

Aspergillosis

Michael J. Satlin, Samantha E. Jacobs, and Thomas J. Walsh

Chapter 34

Mucormycosis

Brad Spellberg and Johan Maertens

Chapter 35

Cryptococcus Infections in Transplant Recipients

Raymund R. Razonable and Pearlie P. Chong

Chapter 36

Histoplasmosis, Coccidioidomycosis and Diseases due to Other Endemic Fungi in Transplant Recipients

Pascalis Vergidis, Chadi A. Hage, and L. Joseph Wheat

Chapter 37

Cytomegalovirus

Amar Safdar and Donald Armstrong

Chapter 38

Epstein-Barr Virus Infection and Post-Transplant Lymphoproliferative Disease

Benjamin E. Gewurz, Amy Sievers, David M.Weinstock, Sheila Mitsuma and Amar Safdar

Chapter 39

Herpes Simplex Viruses 1 and 2, Varicella Zoster Virus and Human Herpes Viruses 6, 7 and 8 in Transplant Recipients

Raymund R. Razonable*

Chapter 40

Respiratory Viral Infections in Transplant Recipients

Catherine Liu, Dora Y. Ho, and Michael Boeckh

Chapter 41

Hepatitis A, B, C

Jonathan Merola, Alexander Z. Jow, and Samuel H. Sigal

Chapter 42

Enterovirus Infection in Immunocompromised Hosts

Joanna Schaenman, Dora Y. Ho, Lindsey R. Baden, and Amar Safdar

Chapter 43

Parvovirus B19

Morgan Hakki and Lynne Strasfeld

Chapter 44

West Nile Virus in Immunocompromised Hosts

Dora Y. Ho, Joanna M.D. Schaenman, and Lindsey R. Baden

Chapter 45

Rare and Emerging Viral Infections in the Transplant Population

Susanna K. Tan, Jesse J. Waggoner, and Stan Deresinski

Chapter 46

Parasitic Infections in Transplant Recipients: Toxoplasmosis, Strongyloidiasis and Other Parasites

Brian G. Blackburn and Jose G. Montoya

Chapter 47

Impacts and Challenges of Advanced Diagnostic Assays for Transplant Infectious Diseases

N. Esther Babady, Yeon Joo Lee, Genovefa Papanicolaou, and Yi-Wei Tang

Chapter 48

Diagnosis of Systemic Fungal Diseases

Simon F. Dufresne, Kieren A. Marr and Shmuel Shoham

Chapter 49

Viral Diagnostics

Robin K. Avery and Belinda Yen-Lieberman

Chapter 50

Antibiotic Consideration in Transplant Recipients

Jerry Altshuler, Samuel L. Aitken, Melanie Maslow, John Papadopoulos, and Amar Safdar

Chapter 51

Pharmacokinetics and Pharmacodynamics of Antibiotics in Transplant Patients

Kelly E. Schoeppler, Scott W. Mueller, and Gerard R. Barber

Chapter 52

Antifungal Consideration for Transplant Recipients

Yanina Dubrovskaya, Man Yee Merl, David S. Perlin, and Amar Safdar

Chapter 53

Immunomodulatory Properties of Antifungal Agents on Immune Functions of the Host

Maria Simitsopoulou and Emmanuel Roilides

Chapter 54

Antiviral Consideration for Transplantation Including Drug Resistance

Sunwen Chou and Nell S. Lurain

Chapter 55

Pharmacokinetics and Pharmacodynamics of Antiviral Drugs in Special Population

Marco R. Scipione* and John Papadopoulos

Chapter 56

Anti-Mycobacterial Consideration in Transplantation Including Drug Non-Susceptibility and Resistance: Tuberculosis and Nontuberculous Mycobacterial Disease

Julie V. Philley and David E. Griffith

Chapter 57

Adaptive Immunotherapy for Opportunistic Infections

Aspasia Katragkou, Thomas J. Walsh, and Emmanuel Roilides

Chapter 58

Immunotherapy for Invasive Mold Disease in Transplant Patients - Dendritic Cell Immunotherapy, Interferon-gamma, Recombinant Myeloid Growth Factors, and Healthy Donor Granulocyte Transfusions

William K. Decker, Matthew M. Halpert, Vanaja Konduri, Dan Liang, Christopher N. Hampton, and Amar Safdar

Chapter 59

Antimicrobial Stewardship: Considerations for a Transplant Center

Susan K. Seo and Graeme N. Forrest

Chapter 60

The Use of Palliative Care in Organ Transplant Patients and End of Life Issues

Jenny S. Ayala and Joseph Lowy

Chapter 61

Infection Control Strategies in Transplant Populations

Scott Cutro, Michael Phillips, and Harold W. Horowitz

Chapter 62

Travel and Transplantation

Camille Nelson Kotton and Jose G. Montoya

Chapter 63

Vaccination in Organ Transplant

Lara Danziger-Isakov and Camille Nelson Kotton

Chapter 64

Prevention of Fungal Disease

Shirish Huprikar and John R. Wingard

Chapter 65

Antimicrobial Drug Prophylaxis: Challenges and Controversies

Gaurav Trikha, Marcio Nucci, John R. Wingard and Amar Safdar