Main description:

Prostate cancer is the commonest male cancer with over 5 million survivors in US alone. Worldwide, the problem is staggering and has attracted significant attention by media, scientists and cancer experts.

Significant research, discoveries, innovations and advances in treatment of this cancer have produced voluminous literature which is difficult to synthesize and assimilate by the medical community. Prostate Cancer: A Comprehensive Perspective is a comprehensive and definitive source which neatly resolves this problem. It covers relevant literature by leading experts in basic science, molecular biology, epidemiology, cancer prevention, cellular imaging, staging, treatment, targeted therapeutics and innovative technologies.

Prostate Cancer: A Comprehensive Perspective, is a valuable and timely resource for urologists and oncologists.

Contents:

Contents

Foreword

List of Contributors

Section 1: Basic Scientific Foundation

Editors: John D. Kelly, Hardev Pandha, Maria Shevchuk, Karl-Dietrich Sievert, and Atsushi Takenaka

1. Development, Applied and Surgical Anatomy of the Prostate

Anthony J. Costello and Niall M. Corcoran

2. Molecular Biology and Prostate Cancer

Greg L. Shaw and David E. Neal

3. Endocrine Mechanisms, Androgen Receptor and Carcinogenesis, Hormone Escape

Kaustubh Datta and Donald Tindall

4. Molecular Mechanisms of Castrate Resistant Prostate Cancer

Francois Lamoureux, Amina Zoubeidi, and Martin E. Gleave

5. Immunologic Aspects of Prostate Cancer

Christine Galustian, Oussama Elhage, Richard Smith, and Prokar Dasgupta

6. Stem Cells in Carcinogenesis of the Prostate

Shi-Ming Tu and Sue-Hwa Lin

7. Murine Models of Prostate Cancer

Eric C. Kauffman, Casey K. Ng, and Carrie Rinker-Schaeffer

8. Prostate Cancer and the Metabolic Syndrome

Stephen EM Langley and Jenny P. Nobes

9. Inflammation and Cancer of the Prostate

Sonya Vasto, Emilio Italiano, Vitale Miceli, and Giuseppe Carruba

10. HIV and Prostate Cancer

Matthew S. Wosnitzer, Jennifer J. Ahn, and Franklin C. Lowe

11. Prostate Cancer Genetics

Sashi S. Kommu, Samuel Bishara, and Stephen M. Edwards

12. Gene Expression Profiling and Somatic Genome Changes

Michael Ittmann

13. The Proteomic Approach to Prostate Cancer

Sashi S. Kommu and Emanual Petricoin

14. Epigenetic Changes in Prostate Cancer

William G. Nelson, Michael C. Haffner, Angelo M. De Marzo, and Srinivasan Yegnasubramanian

15. Biomarkers of Potential Therapeutic Value

Hideaki Miyake, Atsushi Takenaka, and Masato Fujisawa

16. Prostate Tissue Banking

Harveer Dev, Prasanna Sooriakumaran, and Ashutosh Tewari

17. Molecular Imaging in Diagnostics

Casey Ng, Eric Kauffman, and Hossein Jadvar

18. Molecular Risk Profiling

Neil E. Martin

19. Premalignant Lesions of the Prostate

Daniel M. Berney and Anne Y. Warren

20. The Pathology of Prostatic Carcinoma

Maria Shevchuk and Brian D. Robinson

21. The Pathology of Non-Epithelial Tumors of the Prostate

Maria Shevchuk and Brian D. Robinson

22. Neuroendocrine Prostate Cancer

Himisha Beltran, Juan Miguel Mosquera, and Mark A. Rubin

Section 2: Epidemiology, Screening, and Chemoprevention

Editors: Neil Fleshner, Cynthia Kuk, William Nelson, and Alexandre Zlotta

23. Epidemiology of Prostate Cancer

Ankur M. Manvar, Raj S. Pruthi, Eric. M. Wallen, and Matthew E. Nielsen

24. Racial Disparities and the Global Picture

James E. Ferguson III, Matthew Nielsen, Eric Wallen, Raj Pruthi

25. Natural History of Prostate Cancer

Paul K. Hegarty and Nicholas J. Hegarty

26. Population-Based Health Systems as a Foundation for Prostate Cancer Control Research: The Cancer Research Network

Mark C. Hornbrook and Joan Holup

27. Screening for Prostate Cancer

David R. Yates and John B. Anderson

28. Next Generation Screening Tests

Jack A. Schalken and Rizal Hamid

29. Diet and Prostate Cancer: A Holistic Approach to Management

Philippa J. Cheetham and Aaron E. Katz

30. Estrogens in Prostate Cancer

Giuseppe Carruba

31. Vitamin D and Prostate Cancer

Naomi Smith and Alejandro Nolazco

32. The Role of 5a-Reductase Inhibitors (5-ARIs) in Prostate Cancer Chemoprevention

David Margel and Neil Fleshner

33. Other Pharmaceutical Agents in the Chemoprevention of Prostate Cancer

Vivekanandan Kumar

Section 3: Diagnosis and Staging

Editors: Peter Carroll and Gary Dorfman

34. Early-Detection and Patient Risk Stratification in Prostate Cancer

Rajesh Nair, John Withington, Sukanya Ghosh, and Alastair Henderson

35. Tumor Markers

Diederick Duijvesz and Guido Jenster

36. Prostate Specific Membrane Antigen-Based Diagnostics

Joseph Osborne, Scott T. Tagawa, Shankar Vallabhajosula, Stanley J. Goldsmith, and Neil H. Bander

37. Prostate Specific Membrane Antigen-Based Therapeutics

Scott T. Tagawa, Joseph Osborne, Shankar Vallabhajosula, Stanley J. Goldsmith, and Neil H. Bander

38. Presentation and Symptomatology of Prostate Cancer

Agnieszka Michael and Hardev Pandha

39. The Role of Ultrasonography

Suzanne van den Heuvel, Paul C.M.S. Verhagen, and Chris H. Bangma

40. The Use of Magnetic Resonance Imaging in the Management of Prostate Cancer

Matthieu Durand, Aude Fregeville, Naveen Gumpeni, Abhishek Srivastava, Prasanna Sooriakumaran, Siobhan Gruschow, Niyati Harneja, Kristin M. Saunders, Jean Amiel, and Ashutosh K. Tewari

41. The Role of Functional Magnetic Resonance Imaging Techniques

Pieter J. De Visschere, Gert O. De Meerleer, Nicolaas Lumen, and Geert M. Villeirs

42. Prostate Biopsy

Paras B. Singh, Caroline M. Moore, and Mark Emberton

43. The Staging of Prostate Cancer

Benjamin J. Challacombe and Giles Rottenberg

44. Nuclear Medicine in Prostate Cancer

Vinayaka Moorthy Majuran, Vidhiya Vinayakamoorthy, and Derek Svasti-Salee

45. Nanotechnology and Prostate Cancer

Sashi S. Kommu, Lidong Qin, Louis Brousseau, Amrith Rao, Philippe Grange, and Mauro Ferrari

Section 4: Risk Assessment and Decision-Making Strategies for Localized Prostate Cancer

Editor: Matthew Cooperberg

46. Disease Risk Stratification

Alistair Henderson

47. Nomograms in Prostate Cancer

Carvell T. Nguyen and Michael W. Kattan

48. Comparative Effectiveness of Treatment Alternatives for Localized Prostate Cancer

Matthew R. Cooperberg

Section 5: Management of Localized Disease

Editors: Prokar Dasgupta, Alex Mottrie, Abhay Rane, Joseph Smith, Datta Wagle, and Peter Wiklund

49. Radical Treatment for Localized Disease: An Overview of Options and Strategies for Decision Making

Joseph A. Smith, Jr.

50. Quality of Life and Management of Localized Disease

Andreas E. Nilsson, Gunnar Steineck, and N. Peter Wiklund

51. Active Surveillance for Favorable-Risk Prostate Cancer

Nathan Lawrentschuk and Laurence Klotz

52. Anesthesia for Robotic-Assisted Prostatectomy

Vinod Malhotra and Peter M. Fleischut

53. Retropubic Radical Prostatectomy: The Technique

Hein Van Poppel and Steven Joniau

54. Retropubic Radical Prostatectomy: The Results

Wolfgang Horninger and Jasmine Bektic

55. Radical Perineal Prostatectomy

Rolf Gillitzer and Joachim W. Thuroff

56. Laparoscopic Radical Prostatectomy: The Technique

Christopher Eden and Anthony Hutton

57. Laparoscopic Radical Prostatectomy: The Results

Evangelos Liatsikos, Odysseas Andrikopoulos, Panagiotis Kallidonis, and Jens-Uwe Stolzenburg

58. Robotic Assisted Radical Prostatectomy: The Technique

Sameer Chopra, Abhishek Srivastava, Prasanna Sooriakumaran, and Ashutosh K. Tewari

59. Lymph Node Dissection in Prostate Cancer Surgery

Aaron Bernie, Douglas S. Scherr, and Michael P. Herman

60. External Beam Radiotherapy for Low Risk Prostate Cancer

Gert De Meerleer, Piet Ost, Geert Villeirs, Nicolaas Lumen, and Valerie Fonteyne

61. Prostate Brachytherapy: Low Dose Rate

Peter Grimm

62. Prostate Brachytherapy: High Dose Rate

Carl Salembier and Peter Hoskin

63. Intensity Modulated Radiotherapy

Bridget F. Koontz, Devon Godfrey, and W. Robert Lee

64. Proton Beam Therapy and Novel Radiotherapeutic Approaches to the Treatment of Prostate Cancer

Jeffrey J. Meyer, Jordan A. Holmes, and Ronald C. Chen

65. Prostate Cryotherapy

Mohamed Ismail, Shwan Ahmed, and John Davies

66. Focal Therapies for Localized Prostate Cancer

Louise Dickinson, Hashim U. Ahmed, and Mark Emberton

Section 6: Failure and Management of Recurrent, Locally Advanced, and Advanced Disease

Editors: Andrew Armstrong, Ronald Chen, Richard Stock, and John Sylvester

67. Biochemical Failure in Prostate Cancer

Tian Zhang and Andrew Z. Wang

68. The Phenomenon of PSA Bounce After Radiation Therapy

Peter Acher and Rick Popert

69. Management of Locally Recurrent Disease

Piet Ost, Valerie Fonteyne, Pieter De Visschere, Nicolaas Lumen, and Gert De Merleer

70. Management of High Risk/Locally Advanced Disease

Valerie Fonteyne, Piet Ost, Nicolaas Lumen, Geert Villeirs, and Gert De Meerleer

71. Radiotherapy Plus Hormonal Therapy

Jordan A. Holmes and Ronald Chen

72. Watchful Waiting in Advanced Prostate Cancer

Maria Carmen Mir and Nathan Lawrentschuk

73. Androgen and Androgen Receptor Directed Therapy as Initial Treatment for Prostate Cancer

Bruce Montgomery and Peter S. Nelson

74. Hormone-Based Therapies for Castration Resistant Prostate Cancer

Elahe A. Mostaghel and Peter S. Nelson

75. Toxicity of Androgen Deprivation Therapy in Hormone Sensitive Prostate Cancer

Naveed H. Akhtar, Elan S. Diamond, Nicole Eiseler, and Scott T. Tagawa

76. Chemotherapy and Novel Systemic Approaches in the Treatment of Metastatic Castration Resistant Prostate Cancer

Robyn J. Macfarlane, Chris Hovens, Niall M. Corcoran, and Kim N. Chi

77. Immunotherapy

Nicola E. Annels and Hardev Pandha

78. Bone Health: Prevention of Skeletal Related Events and Palliative Care

Jean-Baptiste Lattouf and Fred Saad

Section 7: Outcomes and Complications After Treatment

Editors: Mark Emberton, Brent Hollenbeck, and Tom Lue

79. Assessment of Treatment Outcomes Following Prostate Cancer Therapy

Paul Cathcart and Mark Emberton

80. Urinary Incontinence

Ted A. Skolarus

81. Erectile Dysfunction

Maarten Albersen and Tom F. Lue

82. Immediate/Early Surgical Complications

Thomas J. Walton and Declan G. Murphy

83. Population-Based Outcomes Following Treatment of Clinically-Localized Prostate Cancer

Blake Evans and Scott M. Gilbert

84. Management of Radiation Adverse Effects

Seth A. Strope

85. Management of Complications Following Minimally Invasive Prostate Cancer Therapy

Paul Cathcart and Anthony J. Costello

Section 8: Management of Emergencies and Palliative Care

Editors: Steven A. Kaplan and Alexis E. Te

86. Prostate Cancer Emergencies

Bethan C. Hickerton, Mohamed Abdulmajed, Manit Arya, and Iqbal S. Shergill

87. Management of Bone Metastases

Keen Hun Tai and Farshad Foroudi

88. Pain Relief in Metastatic Cancer

Odette Spruyt and Natasha Michael

89. The Psycho-Social Impact of Prostate Cancer

Addie Wooten and Heather Siddons

90. Nursing Issues in Prostate Cancer

Helen Crowe