Main description:

This monograph explains prototype of the biomimetic Multi-Spiked Connecting Scaffold (MSC-Scaffold) fixing in the periarticular bone and the components of a new generation of entirely non-cemented resurfacing arthroplasty (RA) endoprostheses. It presents the design, rapid prototyping, and manufacturing of the prototype biomimetic MSC-Scaffold including bioengineering CAD design and modelling, methods and effects of the electro-erosion machining of the needle palisade and so forth.

Features:

Presents the prototype of a new generation resurfacing endoprosthesis of the hip joint.

Explains prototype endoprosthesis as the first worldwide biomimetic design.

Insights into the entire process of bioengineering design and research on this prototype endoprosthesis.

Proposes novel way of fixation of the endoprosthesis components.

Reviews structural and osteoconductive functionalisation of the interspike space of the prototype MSC-Scaffold.

This book is aimed at professionals and graduate students in biomedical engineering, endoprosthesis engineering and surgery, and biomaterials.

Contents:

Chapter 1. Characteristics of contemporary hip resurfacing arthroplasty endoprostheses and their possible postoperative complications. Chapter 2. Idea of entirely non-cemented implantation of the components of hip resurfacing arthroplasty endoprostheses with the multi-spiked connecting scaffold. Chapter 3. Design, rapid prototyping and manufacturing of the biomimetic multi-spiked connecting scaffold prototype for non-cemented resurfacing endoprostheses. Chapter 4. Structural and osteoconductive functionalization of the interspike space of the prototype multi-spiked connecting scaffold. Chapter 5. Formation of osteoinductive and osseointegrative properties of the bone-contacting surface of the multi-spiked connecting scaffold prototype by the electrochemical cathodic deposition of calcium phosphates. Chapter 6. Research on the system of bone and the prototype multi-spiked connecting scaffold in order to design the structural and biomechanical properties of this system. Chapter 7. Pilot study on the prototype multi-spiked connecting scaffold for non-cemented resurfacing endoprostheses in an animal model. Chapter 8. Pilot microCT study of the impact of embedding the multi-spiked connecting scaffold on the density and compressive strength of the subchondral trabecular bone of femoral heads from patients with osteoarthritis. Chapter 9. Summary, conclusions, and final remarks.