Main description:

Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications, Second Edition presents the main findings to date and the important factors to be considered when contemplating resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate.

In the last several decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures.

Contents:

1. Resident Stem Cells in Kidney Tissue
2. Pancreatic Stem Cells
3. Tissue Engineering and the Role of Biomaterial Scaffolds: The Evolution of Cardiac Tissue Engineering
4. Resident Neural Stem Cells
5. Resident Stem Cell in Skin
6. Lung Resident Stem Cells
7. Skeletal Resident Stem Cells
8. Cardiac Stem Cells
9. The Neural Crest and the Stem Cells of Neural Crest
10. Liver Resident Stem Cell
11. Telocytes and Stem Cells
13. Endothelial Progenitors for tissue regeneration
14. Induced Pluripotent Stem Cells as an alternative for tissue repair