Main description:

With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.

Contents:

FOREWORDProf. G. Veerabhadram
PREFACE
Chapter 1: Introduction to active smart nanomaterials for biomedical applicationsJin-Chul KimKangwon National University, Chuncheon, South Korea
Chapter 2: Cancer cell sensing and therapy using affinity tag-conjugated gold nanoparticlesAlle MadhusudhanKangwon National University, Chuncheon, South Korea
Chapter 3: Gold nanoparticles enlighten the future of cancer theranosticsJianfeng GuoSchool of Pharmaceutical Sciences, Jilin University, 1266, Fujin Road, Changchun 130021, China
Chapter 4: Recent advances in hydrogels smart drug delivery systems Sharif AhmadDepartment of Pharmacology, All India Institute of Medical Sciences, India Chapter 5: Carbon-based nanomaterials for biomedical applicationsKai YangState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, China Chapter 6: A new era of cancer treatment: carbon nanotubes as drug delivery toolsAlexander M SeifalianCentre for Nanotechnology and Regenerative Medicine, University, College London, London, UK
Chapter 7: pH- and ion-sensitive materials for control drug delivery Takayuki YoshidaDrug Delivery, Pharmaceutical Research and Technology Labs, Astellas Pharma, Inc., 180 Ozumi, Yaizu, Shizuoka 425-0072, Japan
Chapter 8: Thermo-responsive polymers and their application as smart biomaterialsYukiko T. MatsunagaCenter for International Research on Integrative Biomedical Systems (CIBiS), The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan
Chapter 9: Redox-responsive polymers and their application in drug delivery systemsJohn F. QuinnARC Centre of Excellence in Convergent Bio-Nano Science & Technology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Melbourne, Victoria 3052, Australia
Chapter 10: Recent strategies to explore the biomedical applications of nanocelluloseDinesh KumarKangwon National University, Chuncheon, South Korea
Chapter 11: Tissue engineering using cellulose nanofibrils as Scaffold MaterialAndrew E. PellingSymbioticA, School of Human Sciences, University of Western Australia, Perth, WA, Australia
Chapter 12: Use of solid lipid nanoparticles to improve the oral bioavailability of poor soluble drugsDeepti PanditaDepartment of Pharmaceutics, Jan Nayak Ch. Devi Lal Memorial College of Pharmacy, Sirsa 125055, Haryana, India
Chapter 13: Applications of dendrimers in drug delivery systemsE. BustosCentro de Investigacion y Desarrollo Tecnol ogico en Electroqu imica S.C., Parque Tecnologico Quer etaro s/n, Sanfandila, 76703 Pedro Escobedo, QRO, Mexico
Chapter 14: Liposomes for drug delivery: progress and problemsJin-Chul KimKangwon national University, Chuncheon, South Korea
Chapter 15: Cubosome nanoparticles for enhanced delivery of anticancer drugJana B. NiederDepartment of Nanophotonics, Ultrafast Bio- and Nanophotonics Group, INL - International Iberian Nanotechnology Laboratory, Av. Mestre Jose Veiga s/n, 4715-330, Braga, Portugal
Chapter 16: Layer-by-Layer assemblies for cancer diagnosis and treatment UMR CNRS/INPG 5628 (LMGP), 3 parvis Louis Neel, 38016 Grenoble, France
Chapter 17: Polymeric micelles for drug deliveryAfsanesh Lavasanifar University of Albert, Edmonton, Alberta T6G2N8, Canada
Chapter 18: Role of plant-based materials/gums in developing drug delivery systems B. Sashidhar Rao Department of Biochemistry, Osmania University, Hyderabad, India
Chapter 19: Ethosomes: A novel tool for drug delivery through the skinAmarachinta Padmanabha Rao
Chapter 20: Niosomes as nanoparticular drug carriers: fundamentals and recent applicationsNoufel Samed
Chapter 21: Graphene oxide nanosheets used in photothermal therapyHongjie Dai Department of Chemistry, Stanford University, Stanford, California 94305, United States Chapter 22: Metal doped carbon dots used in bio-imaging and cancer therapyJoydeep DasSchool of Chemistry, Shoolini University of Biotechnology and Management Sciences, Bajhol, PO Sultanpur, Solan, HP, 173229, India
BIBLIOGRAPHY
GLOSSARY
INDEX