Main description:

The book showcases the newest research on smart nanoplatforms responding to "hypoxia"; an omnipresent pathological feature of many modern-day diseases and its potential applications. The book demonstrates the versatility of hypoxia targeted smart nanoplatforms in disease management in diverse pathological settings presented in chapters contributed by various experts in the field. The themes in the book touch upon critical facets to address pathological hypoxia such as nanomaterials enhancing oxygenation, hypoxia responsive nanoformulations which deliver the drug directly to the hypoxic site, limited toxicity and enhanced efficacy of smart nanoformulations to counter molecular consequences of hypoxia, and theranostics combining hypoxia detection systems with drug delivery systems. This book disseminates the current implications of smart nanomaterials in disease management that can be exploited by scholars, researchers, and pharma industries to develop, manufacture, and commercialize hypoxia targeted diagnostics and therapeutics.

Contents:

Bio-inspired nano systems interacting with the host environment: smart nano systems.- Recent progress in hypoxia-targeting: peptide-based nanomaterials.- New developments in nanotheranostics combined with intelligent bioresponsive systems.- Recent advancements in the field of stimuli-responsive nanopolymers for cancer treatment.- Novel Strategies to repress tumor hypoxia for the enhancement of cancer therapy.- Anopoxia: Antimonene-based nanoplatform for precision cancer therapy targeting cancer hypoxia.- Efficacy of diverse oxygen delivering nanoparticles in vitro and in animal models for treating hypoxia.- Anoproteomic: An approach for the identification of molecular targets associated with hypoxia.- Advances of nanomaterial with hypoxia inducible factor in periodontal inflammation.- ROS responsive silica nanoparticles for controlled and targeted drug delivery.- Tissue oxygenation and pH responsive fluorescent nano sensors in tumour diagnosis.- Hypoxia responsive nanomaterials for cerebral ischemia diagnosis.- Multifunctional hypoxia imaging nanoparticles.- Anaerobic bacteria mediated hypoxia-specific delivery of nanoparticles.- Reversible switch ON-OFF responsive nanoparticles in hypoxia management.