Main description:

A practical handbook on fecal microbiota transplantation (FMT) for physicians, nurses, physician assistants, students, residents, and fellows, The 6 Ds of FMT: A Primer for Clinicians from Decision to Discharge and Beyond provides a clinical framework to understand and administer this treatment as safely and effectively as possible.

FMT has emerged as a promising treatment for C. difficile infection (CDI), and there is a major need for educational resources on the topic. Drs. Jessica Allegretti, Zain Kassam, and their expert contributors are leaders in the field and have collectively cared for thousands of patients suffering from recurrent CDI who have benefitted from FMT.

This guide provides practical tools, clinical pearls, and answers to frequently asked questions. Beginning with introductory information on the microbiome and exploring the history of FMT, The 6 Ds of FMT outlines a step-by-step checklist for administering FMT:

Decision: Who is the right CDI patient to receive FMT? What clinical questions should you ask patients in your FMT clinical assessment?
Donor: How do you select and screen a donor for FMT?
Discussion: What are the risks, benefits, and alternatives that need to be discussed with patients?
Delivery: What is the best delivery method for FMT - colonoscopy, nasogastric tube, enema, or capsules?
Discharge and follow-up: What is the ideal post-FMT care? How should you council patients following FMT?
Discovery: What are the most promising emerging clinical applications for FMT? What is the evidence for FMT in obesity, autism, irritable bowel syndrome, inflammatory bowel disease, antibiotic resistant bacteria, and liver disease?

Arming healthcare professionals with the ability to answer questions from patients regarding FMT and the microbiome, The 6 Ds of FMT provides a pragmatic guide for this exciting treatment.

Contents:

Dedication
Acknowledgments
About the Editors
Contributing Authors
Chapter 1 Introduction
Chapter 2 Microbiome 101
Chapter 3 The History of Fecal Microbiota Transplantation
Chapter 4 Decision: Which Patients With Clostridioides difficile Infection Are Appropriate for Fecal Microbiota Transplantation?
Chapter 5 Decision: Considerations for Use of Fecal Microbiota Transplantation in Special Patient Populations
Chapter 6 Donor: How Do You Select and Screen Candidate Donors for Fecal Microbiota Transplantation?
Chapter 7 Discussion: How Do You Discuss the Risks and Benefits of Fecal Microbiota Transplantation?
Chapter 8 Delivery: How Do You Select the Most Appropriate Delivery Modality for Fecal Microbiota Transplantation?
Chapter 9 Discharge: How Should You Follow and Care for Patients After Fecal Microbiota Transplantation?
Chapter 10 Discovery: Emerging Indications
10.1 | Other Clostridioides difficile Indications
10.1.1 | The Role of Fecal Microbiota Transplantation in the Treatment of Primary Clostridioides difficile Infection
10.1.2 | The Role of Fecal Microbiota Transplantation in the Treatment of Severe and Fulminant Clostridioides difficile Infection
10.2 | Gastrointestinal Indications: What Have We Learned?
10.2.1 | The Role of Fecal Microbiota Transplantation in the Treatment of Inflammatory Bowel Disease
10.2.2 | The Role of Fecal Microbiota Transplantation in the Treatment of Pouchitis
10.2.3 | The Role of Fecal Microbiota Transplantation in the Treatment of Irritable Bowel Syndrome
10.3 | The Role of Fecal Microbiota Transplantation in the Treatment of Liver Diseases
10.4 | The Role of Fecal Microbiota Transplantation in the Treatment of Autism Spectrum Disorder
10.5 | The Role of Fecal Microbiota Transplantation in the Decolonization of Antibiotic-Resistant Bacteria
10.6 | The Role of Fecal Microbiota Transplantation in the Treatment of Obesity, Metabolic Syndrome, and Nonalcoholic Fatty Liver Disease
Chapter 11 Frequently Asked Questions
Financial Disclosures
Index