Main description:

Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.

Contents:

Acknowledgements
Preface

Part 1: Nucleolar Structure and Organization
1. Structural organization of the nucleolus as a consequence of the dynamics of ribosome biogenesis
Daniele Hernandez-Verdun

2. The dynamic proteome of the nucleolus
Francois-Michel Boisvert, Yasmeen Ahmad, Angus I. Lamond

3. The Structure of rDNA Chromatin
Peter C McKeown, Peter J Shaw

4. The epigenetics of the nucleolus: structure and function of active and silent ribosomal RNA genes
Raffaella Santoro

5. UBF, an Essential Player in Maintenance of Active NORs and nucleolar formation
Alice Grob, Christine Colleran, Brian McStay

Part 2: Role of the Nucleolus in Ribosome Biogenesis
6. The RNA Polymerase I Transcription Machinery
Renate Voit, Ingrid Grummt

7. Small Ribonucleoproteins in Ribosome Biogenesis
Franziska Bleichert, Susan Baserga

8. Crosstalk between ribosome synthesis and cell cycle progression and its potential implications in human genetic disease
Marie Gerus, Michele Caizergues-Ferrer, Yves Henry, Anthony Henras

9. The multiple properties and functions of nucleolin
Rong Cong, Sadhan Das, Philippe Bouvet

10. The multifunctional nucleolar protein nucleophosmin/NPM/B23 and the nucleoplasmin family of proteins
Shea Ping Yip, Parco M. Siu, Polly H.M. Leung, Yanxiang Zhao, Benjamin Y.M Yung

11. Structure and function of NOPP140 and treacle
Fang He, Patrick DiMario

Part 3: Novel Functions of the Nucleolus
12. Chapter 12. The Role of the Nucleolus in the Stress Response
Laura A. Tollini, Rebecca A. Frum, Yanping Zhang

13. New Frontiers in Nucleolar Research - Nucleostemin and Related Proteins
Robert Tsai

14. Viruses and the Nucleolus
David Matthews, Edward Emmott, Julian Hiscox

15. Assembly of Signal Recognition Particles in the Nucleolus
Marty Jacobson

16. Relationship of the Cajal Body to the Nucleolus
Andrew Gilder, Michael Hebert

17. Role of the Nucleolus in HIV Infection and Therapy
Jerlisa Arizala, John Rossi