Main description:

A review of the full scope of research on the neurological and neurobehavioral implications of neuro-AIDS including the fields of microbiology and immunology.

Considers the broad scope of effects of HIV/AIDS on the brain and peripheral nervous system (neuro-AIDS), both pre- and post-HAART era.
Links basic pathology and pathophysiology research with clinical findings, diagnostic, and assessment techniques in both the CNS and the periphery.
Examines the wide range of HIV-associated comorbidities including fungal, viral, syphilitic, and Toxoplasma infections.
Covers neurological and neurobehavioral syndromes (dementia, delirium, depressive disorders, fatigue, and peripheral nervous and muscular dysfunction), including diagnosis and treatment.
Presents specific information on neuro-AIDS in special populations including women, children, minorities, and older individuals.
Explores medico-legal issues, including end-of-life concerns specific to neuro-AIDS patients.
Examines the status of neuro-AIDS conditions at the global level.

This title is published by the American Society for Microbiology Press and distributed by Taylor and Francis in rest of world territories.

Contents:

Table of Contents

Section I. Disorders Due to Primary HIV-1 Pathogenesis and Their Treatment

1. HIV-1-Associated Neurocognitive Disorders in the HAART Era, Karl Goodkin, Aaron Aronow, Gayle Baldwin, Rebeca Molina, and Wenli Zheng

2. Evolution of Neuropsychological Issues in HIV-1 Infection during the HAART Era, Thomas D. Marcotte and J. Cobb Scott

3. HIV Infection and Stroke: the Changing Face of a Rising Problem, Mauricio Concha and Alejandro Rabinstein

4. HIV-Associated Myelopathy, Myopathy, and Meningitis, Lydia Estanislao

5. Investigation and Presentation of Autonomic Neuropathies in HIV Infection, Roy Freeman and Rachel Nardin

6. Distal Sensory Polyneuropathy and Other Selected Neuropathies in HIV Infection, Lydia Estanislao, Anthony Geraci, and David Simpson

7. Mitochondrial Dysfunction and Lactic Acidosis in HIV Disease, Ashok Verma and Jorge Pardo

8. Neurologic Outcomes in HIV Infection: Clinical Events and Surrogate Markers, Constantin T. Yiannoutsos

9. Designing HIV gp120 Peptide Vaccines: Rhetoric or Reality for Neuro-AIDS? Pandjassarame Kangueane, Rajarathinam Kayathri, Meena Kishore Sakharkar, Darren R. Flower, Kristen Sadler, Francesco Chiappeli, David M. Segal, and Paul Shapshak

Section II. Pathophysiological Issues

10. Neurovirological Aspects of HIV Infection in the HAART Era, Zahida Parveen, Edward Acheampong, Roger J. Pomerantz, and Muhammad Mukhtar

11. Neuroimmunology and the Pathogenesis of HIV-1 Encephalitis in the HAART Era: Implications for Neuroprotective Treatment, Seth W. Perry and Harris A. Gelbard

12. Chemokines and the Neuropathogenesis of HIV-1 Infection, Dawn Eggert, Eric Anderson, Jialin Zheng, and Howard E. Gendelman

13. Cerebrospinal Fluid Markers in the Management of Central Nervous System HIV Infection and the AIDS Dementia Complex, Magnus Gisslen, Lars Hagberg, Paola Cinque, Bruce Brew, and Richard W. Price

14. The Neuropathology of HIV Pre- and Post-HAART, Jutta K. Neuenburg

15. The Role of Viral Genetic Variability in HIV-1-Associated Neurocognitive Disorder, Paul Shapshak, Alireza Minagar, Pandjassarame Kangueane, Simon Frost, Sergei L. Kosakovsky Pond, Selene Zarate, Elyse Singer, Deborah Commins, Anne De Groot, Miguel Quinones-Mateu, and Ernest Terwilliger

16. Antioxidants and Brain Function in HIV/AIDS, Gail Shor-Posner, Adriana Campa, Maria-Jose Miguez-Burbano, Gloria Castillo, and Geraldine Moren-Black

17. Cell Cycle Proteins and the Pathogenesis of HIV-1 Encephalitis in the HAART Era, Kelly L. Jordan-Sciutto and Cagla Akay

Section III. Neuroimaging in HIV Infection

18. The Uses of Structural Neuroimaging in the Brain in HIV-1-Infected Patients, Majda M. Thurnher and M. Judith Donovan Post

19. Functional Magnetic Resonance Imaging in HIV-Associated Dementia, Thomas Ernst, Dardo Tomasi, and Linda Chang

20. Magnetic Resonance Spectroscopy in HIV-Associated Brain Injury, Linda Chang, Kai Zhong, and Thomas Ernst

Section IV. HIV Comorbidities

21. Hepatitis C Virus: Variability, Extrahepatic Replication, and Neuroinvasion, Marek Radkowski, Jonathan Nasseri, and Tomasz Laskus

22. Toxoplasmosis of the Central Nervous System, Katia V. Brown and Daniel J. Skiest

23. Basic and Clinical Aspects of Human Cytomegalovirus Infection, Robert R. McKendall and Alex Tselis

24. Cryptococcosis and Other Fungal Infections of the Central Nervous System, Roger J. Bedimo and Daniel J. Skiest

25. Neurosyphilis in AIDS, Joseph R. Berger and Aaron J. Berger

26. Progressive Multifocal Leukoencephalopathy in the Era of HAART, David B. Clifford

27. Epstein-Barr Virus Infection and Primary Central Nervous System Lymphoma, Alex Tselis and Robert R. McKendall

28. Mood Disorders, Delirium, and Other Neurobehavioral Symptoms and Disorders in the HAART Era, Stephen J. Ferrando and Todd Loftus

29. Substance Use Disorders and Neuro-AIDS in the HAART Era, Jeffrey A. Rumbaugh and Avindra Nath

Section V. Special Populations and Neuro-AIDS

30. Ethnicity and Neuro-AIDS Conditions in the HAART Era, Loyda M. Melendez, Raul Mayo-Santana, Carlos Luciano, and Valerie Wojna

31. Women and Neuro-AIDS Conditions in the Era of HAART, Gabriele Arendt, Y. Jaeger, and Th. Nolting

32. Pediatric Neuro-AIDS, Anita L. Belman

33. Interaction of the Aging Process with Neurobehavioral and Neuro-AIDS Conditions in the HAART Era, Karl Goodkin, Mauricio Concha, Beth D. Jamieson, Rosa Rebeca Molina, Enrique Lopez, Wenli Zheng, Deshratn Asthana, and W. David Hardy

Section VI. Special Health Care Issues and Neuro-AIDS

34. Neurologic Aspects of Palliative Care for HIV/AIDS, Peter A. Selwyn and John Booss

35. Medico-Legal Issues in HIV/AIDS in the 21st Century, Soma Sahai-Srivastava

36. Global Issues in Neuro-AIDS and Their Evolution over the Future of the HAART Era, Bruce J. Brew