Main description:

The 2nd edition of this book incorporates the tremendous clinical advances that have occurred in the field of transcranial direct current stimulation (tDCS) over the past 5 years. Since the 1st edition was published, the clinical use of tDCS has moved from its infancy, and is now in a thrilling new phase with numerous possibilities as well as challenges.

tDCS is a technique that excels in terms of safety and tolerability, and within a few years, novel technological developments will allow its use at home. At the same time, large, phase III trials have been exploring the clinical efficacy of tDCS, the results of which have been published in leading journals such as the New England Journal of Medicine and JAMA Psychiatry.

This 2nd edition summarizes the state of the art of the field. Written by leading experts in the field, the book is divided into 5 parts: Introduction and Mechanisms of Action; Research Methods; tDCS in the life cycle; Applications of tDCS in neuropsychiatric disorders (further divided into Psychiatry and Neurology); and The clinical use of tDCS.

It also includes several new chapters, covering topics such as precision stimulation of tDCS; combination of tDCS with different neuroimaging modalities; and use of tDCS in new clinical conditions. Moreover, all chapters have been rewritten and updated.

This book will be of significant interest to psychiatrists, neurologists and neuroscientists new to the field as well as those with a background in tDCS who want to increase their understanding of particular psychiatric conditions.

Contents:

Part I. Introduction and mechanisms of actionChapter 1. Historical aspects of transcranial electric stimulation

Chapter 2. Basic mechanisms of transcranial alternating current and random noise stimulation

Chapter 3. Physiology of transcranial direct and alternating current stimulation

Chapter 4. Animal Models of tES: Methods, Techniques and Safety

Chapter 5. Animal Studies on the Mechanisms of Low-Intensity Transcranial Electric Stimulation

Part II. Research Methods

Chapter 6. TMS-evoked EEG Response in Neuropsychiatric Disorders

Chapter 7. Multimodal Association of tDCS with Electroencephalography

Chapter 8. tDCS and Magnetic Resonance Imaging

Chapter 9. tDCS and Functional Connectivity

Chapter 10. The value of neuroimaging for treating depression with brain stimulation

Chapter 11. Target Engagement with Transcranial Current Stimulation

Chapter 12. Cerebellar and Spinal tDCS

Chapter 13. Precision targeting of neural networks with tDCS informed by brain mapping

Chapter 14. Clinical research and methodological aspects for tDCS research

Part III. TDCS in the life cycle

Chapter 15. tDCS in Child and Adolescent Psychiatry

Chapter 16. Transcranial Direct Current Stimulation in the perinatal period

Chapter 17. Modulating Cognition in Healthy Young Adults with tDCS

Chapter 18. tDCS in exercise, sport performance and recovery process

Chapter 19. Transcranial Direct Current Stimulation in Social and Emotion Research

Chapter 20. Neurodegenerative cognitive disorders

Part IV. Applications of tDCS in neuropsychiatric disorders

Chapter 21. Mood disorders: clinical results

Chapter 22. Effect of transcranial direct current stimulation on hallucinations in patients with Schizophrenia

Chapter 23. Schizophrenia: Negative Symptoms

Chapter 24. OCD, Anxiety Disorders, and PTSD

Chapter 25. Cognitive functions in substance-related and addictive disorders

Chapter 26. Transcranial Direct Current Stimulation in Substance Use Disorders

Chapter 27. Attention-deficit/hyperactivity disorder

Chapter 28. Cognitive effects of transcranial direct current stimulation in clinical trials

Chapter 29. Epilepsy

Chapter 30. Pain syndromes

Chapter 31. Transcranial direct current stimulation for the treatment of tinnitus

Chapter 32. Transcranial direct current stimulation in disorders of consciousness

Chapter 33. TDCS in the Context of Rehabilitation

Part V. The clinical use of tDCS

Chapter 34. Safety and tolerability

Chapter 35. Home-based tDCS: applications and approaches, design, feasibility and safety

Chapter 36. Ethical Aspects of tDCS Use in Neuropsychiatry and the Risk of Misuse

Chapter 37. tDCS-Pharmacotherapy interactions

Chapter 38. Combination of tDCS with Psychotherapy and Neurobehavioral Interventions: Systematic Review and Mechanistic Principles for Future Clinical Trials

Chapter 39. Regulatory aspects