Main description:

Translational Autoimmunity: Advances in Autoimmune Rheumatic Diseases, Volume Six addresses autoimmune diseases classified under the category of rheumatic diseases. Rheumatic diseases are heterogeneous groups of disorders in which inflammation affects not only joints, but also tendons, ligaments and bones. This updated release focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, osteoarthritis and Sjogren's syndrome, and will be of interest to researchers, students and clinicians interested in autoimmune diseases, especially rheumatic diseases.

From an introduction to rheumatic diseases to diagnostic laboratory tests, and from the microbiota-immunity to cell-based therapies, the bench to bedside approach to rheumatic diseases is the main subject of discussion in this comprehensive resource.

Contents:

1. Introduction on Autoimmune Rheumatic Diseases
2. Bone health in autoimmune inflammatory rheumatic diseases
3. Rheumatic diseases: from bench to bedside
4. Rheumatic fever: from pathogenesis to vaccine perspectives
5. Changes in future rheumatoid arthritis treatment in the light of Epstein-Barr virus infection
6. Rheumatologic diseases: the microbiota-immunity axis in development and treatment
7. The diagnostic laboratory tests in rheumatic diseases
8. Autoantibody profiling in autoimmune rheumatic diseases: from basic research to clinical use
9. Air pollution and rheumatoid arthritis: current knowledge and state-of-the-art
10. Advanced therapies for rheumatoid arthritis
11. A tolerogenic dendritic cell-based therapy targeting heat shock protein specific regulatory T cells in rheumatoid arthritis
12. T-cell large granular lymphocytic leukemia in the setting of rheumatoid arthritis
13. Biomaterials as tools for re-balancing the skewed immunity in rheumatoid arthritis
14. Immunopathogenesis of systemic lupus erythematosus
15. Challenges in systemic lupus erythematosus: from bench to bedside
16. Therapeutic potential in systemic lupus erythematosus
17. The pathology and potential clinical applicability of interfering T cells in systemic lupus erythematosus
18. Rheumatic chorea
19. Management of the rheumatoid hind foot and ankle
20. Immunopathogenesis of scleroderma
21. Skin manifestations and autoimmune disturbances in dermatomyositis
22. T cells in systemic sclerosis
23. Etiopathogenesis of Behcet's disease: the role of genetic, immunological and environmental factors
24. Interleukin-1 family in Behcet's disease: inflammatory and anti-inflammatory mediators
25. Salivary gland regeneration and repair in Sjogren's syndrome
26. Translational regulation of bone and joint inflammation by type 2 innate lymphoid cells
27. Arboviruses (Alphavirus) related to autoimmune rheumatic diseases: Triggers and possible therapeutic interventions
28. Rheumatologic manifestations of autoinflammatory disorders