Main description:

This volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiac mechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.

Contents:

Preface - Markus Hecker and Dirk Duncker

1) Hemodynamics and vascular remodeling - Timothy Secomb, Tuscon

2) The biomechanics of venous remodeling - Hanna KUK, Christina Jeanneret, Thomas Noppeney and Thomas Korff, Heidelberg

3) New kids on the block: the emerging role of YAP/TAZ in vascular cell mechano-
transduction - Karl Sward, Sebastian Albinsson and Catarina Rippe, Lund and Stefano Piccolo, Padua

4) GPCRs und flow and pressure - Ursula Storch, Thomas Gudermann and Michael Mederos y Schnitzler, Munchen

5) Biomechanics in small artery remodeling - Erik Bakker and Ed van Bavel, Amsterdam

6) Contributions of wall stretch and shear stress to vascular regulation: Molecular mechanisms of homeostasis and expansion - Ranganath Maringanti, Elana Meijer, Maarten M Brandt, Dirk J. Duncker and Caroline Cheng, Rotterdam

7) Mechanobiology of lymphatic vessels - Anish Mukherjee and Brendon Dixon, Atlanta

8) Hemodynamic control of endothelial cell fates in development - Hanna M Peacock, Margo Daems and Elizabeth AV Jones, Leuven

9) Mechanical regulation of epigenetic modifications in vascular biology and pathobiology - Shu-Yi Wei and Jeng-Jiann Chiu, Taipeh

10) Mechanosensing and mechanotransduction in pulmonary hypertension - Siyu Tian, Jarno J Steenhorst, Kim van der Heiden and Daphne Merkus, Rotterdam

11) Mechanobiology of arterial hypertension - Cor de Wit, Lubeck

12) Mechanobiology of atherosclerosis - Andreas H Wagner, Heidelberg

13) Exploitation of vascular mechanobiology for cardiovascular therapy - Wei Tan, Boulder, CO