Main description:

Venous Ulcers, Second Edition, provides a comprehensive synthesis of evidence-based recommendations and the highest level of expertise from a leading group of doctors, which is a fundamental constituent for the appropriate management of nonhealing venous wounds in everyday practice. This book offers a fertile environment for a complete understanding of genetics and molecular and biochemical mechanisms that lead to the development and progression of venous ulcers, which is essential for elucidating the underlying pathophysiology and can be utilized for developing novel therapies and accessing previously inaccessible areas of research. Socioeconomic impact, impact on health-related quality of life, the clinical course of the disease, and diagnostic algorithms are elaborated in detail. All currently available treatment modalities are explained in a clinically applicable approach with particular emphasis on operative technique, technical feasibility, success rates (both clinical and technical), and side effects. Lastly, this book elaborates on special diagnostic considerations and management of the most complex patients, often requiring the highest level of expertise for successful treatment.

Contents:

Section 1: Chronic venous insufficiency - basic considerations 1. Pathophysiology of chronic venous disease: genetic, molecular and biochemical mechanisms 2. Venous hemodynamics and microcirculation in chronic venous insufficiency 3. Venous ulcers of the lower extremity: etiology, risks and predictive factors 4. Venous ulcers of the lower extremity: epidemiology and socio-economic burden

Section 2: Clinical evaluation and diagnostic modalities 5. Initial clinical evaluation in patients with chronic venous insufficiency 6. Ultrasound evaluation of lower extremity chronic venous disease 7. The diagnosis of major venous outflow obstruction in chronic venous insufficiency 8. Hypercoagulable states associated with chronic venous insufficiency 9. The chronically swollen leg with ulcers - finding the cause: theory and practice 10. Lower extremity wounds associated with mixed venous and arterial insufficiency and relevant differential diagnosis 11. Assessment tools and wound documentation for patients with chronic venous insufficiency

Section 3: Non-operative management of chronic venous insufficiency and wound care 12. Compression therapy in venous leg ulcers 13. Wound healing: adjuvant therapy and treatment adherence 14. Negative pressure wound healing for venous ulcers 15. Medical therapies for chronic venous insufficiency 16. Treatment modalities for the management of nonhealing wounds in patients with chronic venous insufficiency 17. Deep vein thrombosis and prevention of postthrombotic syndrome 18. Improving treatment outcomes - management of coexisting comorbidities in patients with venous ulcers 19. Emerging modalities in local treatment of venous ulcers: advanced dressings, bioengineering, and biologics

Section 4: Operative and endovascular procedures for chronic venous insufficiency 20. Benefits of superficial venous intervention (surgery or endovenous ablation) in the treatment of venous leg ulceration 21. Superficial surgery and perforator interruption in the treatment of venous leg ulcers 22. Endovascular techniques for superficial vein ablation in treatment of venous ulcers 23. Treatment of chronic venous insufficiency with foam sclerotherapy 24. Ultrasound guidance for endovenous treatment 25. Iliac vein stenting in venous leg ulcers 26. Venous valve reconstructions in patients with severe chronic venous insufficiency

Section 5: Special considerations 27. Treatment of recalcitrant venous ulcers with free tissue transfer for limb salvage 28. Management of venous ulcers in patients with congenital vascular malformations 29. Lymphatic disorders in pathogenesis of chronic venous insufficiency