Main description:

This book focuses on the important discoveries of the small molecule-, peptide-, and protein-based virus entry inhibitors and discusses advance of the development of different type of virus entry inhibitors as a novel class of antiviral drugs for treatment and prevention of viral infection. It includes entry inhibitors of HIV,HeV, NiV, RSV, EBOV, HCoV, HBV, HCV, HDV, HPV, flavivirus and influenza virus, so on. This book aims at providing an updated knowledge on virus entry inhibitors.

Contents:

Peptide virus entry inhibitors: past, present and future.- Small-molecule virus entry inhibitors.- Human endogenous virus entry inhibitors.- Lipopeptide HIV entry inhibitors.- Peptide HIV entry inhibitors targeting gp41 NHR.- Small-molecule HIV entry inhibitors targeting gp41 MPER.- Small-molecule HIV entry inhibitors targeting CD4-binding site in gp120.- Small-molecule HIV entry inhibitors targeting gp120.- SARS-CoV, MERS-CoV, and pan-coronavirus entry inhibitors.- Hendra virus (HeV) and Nipah virus (NiV) entry inhibitors.- Ebola virus entry inhibitors.- Cyclo-peptide-based Ebola virus entry inhibitors.- Influenza virus entry inhibitors.- Parainfluenza virus entry inhibitors.- Zika virus entry inhibitors.- HBV entry inhibitors.- HBV and HDV entry inhibitors.- HCV entry inhibitors.- Protein-based HPV entry inhibitors.