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MORE ABOUT THIS BOOK
Main description:
This book provides the first comprehensive overview on the different aromatase inhibitors. Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not very potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency.
Contents:
Background and development of aromatase inhibitors.- Aromatase inhibitors and models for breast cancer.- Clinical pharmacology of aromatase inhibitors.- Clinical studies with exemestane.- Clinical studies with letrozole.- Clinical studies with anastrozole.- The third-generation aromatase inhibitors: a clinical overview.- Lessons from the ArKO mouse.- Possible additional therapeutic uses of aromatase inhibitors
PRODUCT DETAILS
Publisher: Springer (Birkhauser Verlag AG)
Publication date: December, 2007
Pages: 199
Weight: 454g
Availability: Available
Subcategories: Diseases and Disorders, Oncology, Pharmacology
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