Main description:

This book presents a complete up-to date description of cavernoma disease together with its known biology, genetics and variable clinical presentation. It facilitates improved decision-making on surgical intervention by presenting different cases, highlighting the particular features of lesions such as anatomical location, eloquences of adjacent brain and type of presentation that are important when making decisions. In addition, the reader is brought up to speed with developments in the neuroimaging and active treatment techniques, especially surgical resection and radiosurgery. Finally, the natural history of the disease is taken into account and compared to the possible benefits of surgical treatment.

Cavernomas of the CNS: Basic Science to Clinical Practice provides a comprehensive overview from the fundamentals of this condition, to special patient groups such as children and pregnant women. Therefore, it is an indispensable resource for neurovascular surgeons, neurosurgical residents and neurologists.

Contents:

1. Brief History of Cavernous Malformations2. Definition and structure of cerebral cavernous malformations3. Molecular Biology of CCM4. Presentation5. Neuroimaging of Cerebral Cavernous Malformations6. Natural history of cavernous malformations7. Hemispherical Cavernomas in non-eloquent and eloquent areas 8. Cavernoma-Related Epilepsy9. Surgery of deep-seated cavernous malformations10. Surgery of brainstem and cerebellar cavernous malformations11. Stereotactic Radiosurgery of Cavernous Malformations12. Cavernomas in children13. Cavernomas During Pregnancy14. Spinal cavernous malformations15. Intraorbital cavernous malformations