Main description:

In this updated edition, leading medical specialists critically review for the general practitioner the latest techniques for the clinical management of diabetic neuropathy. The contributors focus on the practical aspects of diabetic neuropathy and describe in detail the treatments that are currently available or expected to become available in the near future. They also include concise discussions of the pathogenesis of diabetic neuropathy.

Contents:

Table of Contents - Diabetic Neuropathy

1. History of Diabetic Neuropathy
Vladimir Skljarevski / Alberto Lledo

2. Epidemiology of Diabetic Neuropathy
Stephanie Wheeler / Nalini Singh / Edward J Boyko

3. Genomics of Diabetic Neuropathy
Andrew G Demaine / Bingmei Yang

4. Transgenic and Gene Knockout Analysis of Diabetic Neuropathy
Sookja K. Chung / Stephen S.M. Chung

5. Hyperglycemia-Initiated Mechanisms
Irina Obrosova

6. Effectors - Sonic Hedgehog and p38 Mitogen-Activated Protein Kinase
Sally A Price / Rebecca C Burnarnd / David Tomlinson

7. Neuronal and Schwann Cell Death in Diabetic Neuropathy
James W Russell / Rita M Cowell / Eva L Feldman

8. Metabolic-Functional-Structural Correlations in Somatic Neuropathies in the Spontaneously Type 1 and Type 2 Diabetic BB-Rats
Anders A.F. Sima / Weixian Zhang / Hideki Kamiya

9 Experimental Diabetic Autonomic Neuropathy
Phillip A Low

10 Spinal Cord: Structure and Function in Diabetes
Andrew P Mizisin / Corinne G Jolivalt / Nigel A Calcutt

11 Diabetic Encephalopathy
Geert Jan Biessels

12 Microangiopathy, Diabetes and the Peripheral Nervous System
Douglas W Zochodne

13 Pathogenesis of Human Diabetic Neuropathy
Rayaz Malik / Aristidis Veves

14 Clinical Features of Diabetic Polyneuropathy
Solomon Tesfaye

15 Micro- and Macrovascular Disease in Diabetic Neuropathy
Aristidis Veves / Antonella Caselli

16 Clinical Diagnosis of Diabetic Neuropathy
Vladimir Skljarevski / Rayaz A Malik

17 Punch Skin Biopsy
Michael Polydefkis

18 Aldose Reductase Inhibitors for the Treatment of Diabetic Neuropathy
Aristidis Veves

19 Other Therapeutic Agents
Gary L Pittenger / Henri Parson / Jagdeesh Ullal / Aaron Vinik

20 Pathophysiology of Neuropathic Pain
Misha-Miroslav Backonja

21 Treatment of Painful Diabetic Neuropathy
Andrew J.M. Boulton

22 Focal and Multi-Focal Diabetic Neuropathy
Gerard Said

23 Hypoglycemia and the Autonomic Nervous System
Roy Freeman

24 Cardiovascular Autonomic Neuropathy
Martin J Stevens

25 Postural Hypotension and Anhidrosis
Phillip A Low

26 Gastrointestinal Syndromes Due to Diabetes Mellitus
Juan R Malagelada

27 Genitourinary Complications
Dan Ziegler / Christian Stief

28 Management of Diabetic Foot Complications
T.E. Lyons