Main description:

Bacterial diarrheal diseases remain an important leading cause of preventable death, especially among children under five in developing countries. In the American continent, diarrheal disease and other health complications caused by Escherichia coli constitute a major public health problem, and, therefore, several research groups have dedicated their effort to understand this pathogen and provide feasible solutions to prevent, treat and reduce E. coli infections.

The Latin American Coalition for Escherichia coli Research (LACER) was created as a multidisciplinary network of international research groups working with E. coli with the ultimate goal of advancing understanding of E. coli, and to prepare the next generation of American E. coli investigators. As such, this book compiles the knowledge of these investigators about E. coli, a commensal bacteria living inside its host, and a pathogen causing disease in animals and humans.

Escherichia coli in the Americas contains a series of 15 chapters written by experts, covering basic concepts regarding the different categories of E. coli, including their environmental niche, virulence mechanisms, host reservoir, and disease outcomes, as well as diagnosis, vaccine development and treatment. This book's target audience include trainees and students learning about the basic and clinical aspects of E. coli pathogenesis, as well as experts around the globe who wish to learn more about this pathogen and the public health impact this bacteria has in America.

Contents:

1. Enterotoxigenic Escherichia coli.- 2. Enteroaggregative Escherichia coli (EAEC).- 3. Typical Enteropathogenic Escherichia coli.- 4. Atypical Enteropathogenic Escherichia coli.- 5. Enterohemorrhagic (Shiga toxin-producing) Escherichia coli.- 6. Diffusely Adherent Escherichia coli.- 7. Escherichia coli in Animals.- 8. Escherichia coli in Food Products.- 9. Extra-intestinal Escherichia coli (Uropathogenic E. coli and Avian Pathogenic E. coli).- 10. Secretion Systems of Pathogenic Escherichia coli.- 11. Therapeutics and Vaccines Against Pathogenic Escherichia coli.- 12. Homeostasis vs Dysbiosis: Role of Commensal Escherichia coli in Disease.- 13. Antibiotic Resistance in Escherichia coli.- 14. Interactions of Pathogenic Escherichia coli With Host Receptors.- 15. Human Diarrheal Infections: Diagnosis of Diarrheagenic Escherichia coli Pathotypes.