Main description:

Fatigue is a major symptom in patients with multiple sclerosis (pwMS) and is mainly responsible for unemployment, early retirement but also social withdrawal. This book combines reporting of actually existing scientific knowledge with guidance for clinical practice. As such the book helps health care professionals in all countries to better understand fatigue symptoms but also to help patients to better cope with them.

Contents:

Part Background: 1 Fatigue a phenomenon of modern age? On the history of fatigue2 Definitions, Epidemiology and etiological factors3 Pathophysiology and differentiation to other symptoms and diseases4 Immunopathology and pathogenesisPart Clinic: 5 Motor fatigue and fatigability in MS.6 Cognitive fatigue7 Personality factors and motivation8 Fatigue and depression9 Sleep-wake disordersPart Diagnostics 10 Clinical assessment instruments of fatigue11 Imaging methods and fatigue12 Electrophysiology and fatigue13 Expert opinion and sociomedical evaluationPart Therapy14 Disease modifying drugs and fatigue15 Symptomatic pharmacotherapy and fatigue.16 Non-pharmacological treatment and neurorehabilitation.