Main description:

A state-of-the-art review of the current research. * Explains the history of the disease, and examines how scientists, clinicians, and public health workers have responded to the challenges presented by HIV/AIDS in the 25 years since its recognition. * Explores potential approaches for therapy, including a vaccine for the prevention of HIV infection and AIDS. * Serves as a valuable reference for students, researchers, clinicians, and health care providers.

This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.

Contents:

Table of Contents

1. Discovery, Structure, and Origin of HIV

2. Features of HIV Transmission

3. Steps Involved in HIV: Cell Interaction and Virus Entry
4. Acute HIV Infection and Cells Susceptible to HIV Infection

5. Intracellular Control of HIV Replication

6. Cytopathic Properties of HIV

7. Viral Proteins Determining Biologic Features of HIV

8. Effect of HIV on Various Tissues and Organ Systems in the Host

9. Innate Immune Responses in HIV Infection

10. Humoral Immune Responses to HIV Infection

11. T-Lymphocyte Immune Responses in HIV Infection

12. HIV Infection and Development of Cancer

13. Overall Features of HIV Pathogenesis: Prognosis for Long-Term Survival

14. Antiviral Therapies

15. Vaccine Development

Appendix I. 1993 Revised Classification System for HIV Infection and Expanded AIDS Surveillance Case Definition for Adolescents and Adults

Appendix II. Clinical Categories

Appendix III. Conditions Included in the 1993 AIDS Surveillance Case Definition

Appendix IV. Other Definitions in HIV Infection: CD4+ T-Lymphocyte Categories