Main description:

Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis.

Contents:

1. An overview of leishmaniasis: historical aspects and future perspectives 2. Leishmaniasis: symptoms, disease, and clinical picture 3. Traditional and advanced strategies for the treatment 4. Drug development and resistance in Leishmaniasis 5. Vaccination studies to cure Leishmania Infection 6. Strategies of immune evasion by Leishmania 7. Cell death in Leishmania 8. Stress responses in Leishmania 9. Different in vivo models for the discovery and utility of drug targets and vaccine candidates against leishmaniasis 10. Recent advances in the diagnostic methods of leishmaniasis