Written by an internationally recognized expert in diagnostic breast pathology, this gold-standard text and reference is now in its revised, updated, and expanded Third Edition. It provides a comprehensive, extensively illustrated review of the clinical, radiological, pathological, and therapeutic aspects of the entire spectrum of breast diseases. More than 3,000 full-color illustrations—1,200 new to this edition—provide the true-to-life perspective essential to accurate diagnosis, prognosis, and management. Highlights of this edition include updated information on immunohistochemistry, molecular diagnostics, tissue microarrays, and gene expression profiling; discussion of the advantages and disadvantages of needle core biopsy; descriptions of basal-like carcinoma; and a greatly expanded discussion of pathological and clinical controversies regarding sentinel lymph node mapping.

A companion Website will offer the fully searchable text and an image bank.

Preface

Preface to The First Edition

Acknowledgments

Introduction

Anatomy and Physiological Morphology

Abnormalities of Mammary Growth and Development

Inflammatory and Reactive Tumors

Specific Infections

Papilloma and Related Benign Tumors

Myoepithelial Neoplasms

Adenosis and Microglandular Adenosis

Fibroepithelial Neoplasms

Ductal Hyperplasia: Usual and Atypical

Precancerous Breast Disease: Epidemiological, Pathological and Clinical Considerations

Intraductal Carcinoma

Invasive Duct Carcinoma: Assessment of Prognosis, Morphologic Prognostic Markers, and Tumor Growth Rate

Tubular Carcinoma

Papillary Carcinoma

Medullary Carcinoma

Carcinoma with Metaplasia

Squamous Carcinoma

Mucinous Carcinoma

Apocrine Carcinoma

Mammary Carcinomas with Endocrine Features

Small Cell (Oat Cell) Carcinoma

Secretory Carcinoma

Mammary Carcinoma with Osteoclast Like Giant Cells

Cystic Hypersecretory Carcinoma and Cystic Hypersecretory Hyperplasia

Adenoid Cystic Carcinoma

Cribriform Carcinoma

Lipid-Rich Carcinoma

Glycogen-Rich Carcinoma

Invasive Micropapillary Carcinoma

Paget's Disease of the Nipple

Lobular Carcinoma In Situ and Atypical Lobular Hyperplasia

Invasive Lobular Carcinoma

Unusual Clinical Presentations of Carcinoma

Metastases in the Breast from Non Mammary Malignant Neoplasms

Benign Proliferative Lesions of the Male Breast

Carcinoma of the Male Breast

Breast Tumors in Children

Benign Mesenchymal Neoplasms

Sarcoma

Lymphoid and Hematopoietic Tumors

Pathologic Effects of Therapy

Cutaneous Neoplasms

The Pathology of Axillary and Intramammary Lymph Nodes

Pathologic Examination of Breast and Lymph Node Specimens Including Sentinel Lymph Nodes

Index