Main description:

This new volume written by experts in the field of trypanosome research covers every aspect of trypanosome-vector-host biology. It is a must read for basic researchers working with trypanosomes and related organisms, infection and drug development as well as parasitology in a broader sense.

Contents:

Tsetse fly biology: where it all starts.- Trypanolytic activity of NHS: a first defense.- Antigenic variation: the answer to host immunity.- Early onset of host immunity: the big unknown.- Myeloid cells: parasite control versus pathology.- Adaptive immunity - T cells: old and new views on defense part I.- Adaptive immunity - B cells: old and new views on defense part II.- Proteomics of trypanosomes: what's in there.- Diagnosis: when to treat and when not.- Drug design: the past, the present and future.- Nanobody technology: a novel approach to an old fight.- Sodalis as expression system: using the Trojan horse.- Nagana: it's not all about HAT.