Main description:

Over the past decade, the tumor microenvironment has become one of the most important research areas in cancer biology, as cells within the tumor microenvironment, despite being outnumbered by healthy cells, are able to evade surveillance and immune-mediated destruction. While researchers have learned a great deal about the cellular and structural makeup of the tumor microenvironment, there has been a growing understanding of the metabolic interplay between the tumor micronenvironment's various cellular constituents and how each of them contributes to overall tumor growth and metastases. This new volume will guide researchers, students, oncologists and academics through a rapidly developing and changing field with a thorough understanding of tumor microenvironment biology from a cellular, structural, metabolic, and immunological perspective.

Contents:

1. Inflammatory components of the thyroid cancer microenvironment - an avenue for identification of novel biomarkers

2. Disruption of Cell-Cell Communication in Anaplastic Thyroid Cancer as an Immunotherapeutic Opportunity

3. Exosomes in the Healthy and Malignant Bone Marrow Microenvironment

4. Structural Biology of the Tumor Microenvironment

5. Metabolic interactions between tumor and stromal cells in the Tumor Microenvironment

6. Interacting Genetic Lesions of Melanoma in the Tumor Microenvironment: Defining a Viable Therapy

7. Non-coding RNAs in Papillary Thyroid Cancer: Interaction with cancer associated fibroblasts (CAFs) in the Tumor Microenvironment (TME) and regulators of differentiation and Lymph Node Metastasis