Main description:

Vitamin D: Volume 2: Health, Disease and Therapeutics, Fourth Edition, authoritatively covers the evidence for new roles for vitamin D, ranging from cardiovascular disease, to cancer, diabetes, inflammatory bowel disease, multiple sclerosis and renal disease.

This collection represents a who's who of vitamin D research and the coverage is appropriately broad, drawing in internal medicine, orthopedics, oncology and immunology. Clinical researchers will gain a strong understanding of the molecular basis for a particular area of focus.

Contents:

Volume II: Health, Disease and Therapeutics

Section VII. Population Studies: Vitamin D Deficiency, Nutrition, Sunlight, Genes & Trials 58. Methods of evaluating population studies of vitamin D: strengths & weaknesses 59. Worldwide vitamin D status 60. Vitamin D in Foods: An Evolution of Knowledge 61. Determinants of Vitamin D Deficiency from Sun Exposure: A Global Perspective 62. Vitamin D Fortification and Supplementation Policies to Correct Vitamin D Insufficiency/Deficiency Globally 63. Vitamin D and Food Fortification 64. Bariatric Surgery, Vitamin D, and Bone Loss 65. Genetics of the Vitamin D Endocrine System 66. Randomized Clinical Trials of Vitamin D for the Primary Prevention of Cancer and Cardiovascular Disease, with a Focus on the VITamin D and OmegA-3 TriaL (VITAL)

Section VIII. Disorders 67. Vitamin D deficiency and nutritional rickets in children 68. Vitamin D and Osteoporosis 69. Adult Vitamin D deficiency: fracture & fall prevention 70. Clinical Disorders of Phosphate Homeostasis 71. Vitamin D hydroxylation-deficient rickets, type 1A: CYP27B1 mutations 72. Hereditary 1,25-Dihydroxyvitamin D Resistant Rickets 73. The Role of Genetic Variation in CYP2R1, the Principal Vitamin D 25-hydroxylase, in Vitamin D Homeostasis 74. Infantile Hypercalcemia and CYP24A1 Mutations 75. Drug and Hormone Effects on Vitamin D Metabolism 76. Vitamin D and Organ Transplantation 77. The role of vitamin D in type 2 diabetes and hypertension 78. Vitamin D, obesity and the metabolic syndrome 79. Vitamin D and Renal Disease 80. Calcitriol and Analogs in the Treatment of Chronic Kidney Disease 81. Idiopathic Hypercalciuria and Nephrolithiasis 82. Hypercalcemia Due to Vitamin D Toxicity 83. The Hypocalcemic Disorders 84. Vitamin D: Cardiovascular Effects and Vascular Calcification 85. Vitamin D and Paget's Disease

Section IX. Vitamin D Analogs 86. Analogs of Calcitriol 87. Non-Secosteroidal Ligands and Modulators of VDR 88. Bile acid-derived vitamin D receptor ligands 89. Bifunctional Vitamin D Hybrid Molecules 90. Modulating Vitamin D Receptor-Coregulator Binding with Small Molecules 91. Extended-release Calcifediol in Renal Disease 92. Vitamin D Receptor Antagonists 93. Eldecalcitol and Osteoporosis

Section X. Vitamin D and Cancer 94. Overview of vitamin D actions in cancer 95. Vitamin D Status and Cancer Incidence, Mortality and Prognosis 96. Effects of Vitamin D Derivatives on Differentiation, Cell Cycle and Apoptosis in Hematological Malignancies 97. Vitamin D actions in mammary gland and breast cancer: genomics, metabolism and stem cells 98. Vitamin D Urologic Cancers 99. Vitamin D and Colon Cancer 100. Vitamin D and Skin Cancer 101. Vitamin D and Lung Cancer 102. Vitamin D inflammation and cancer

Section XI. Immunity, Inflammation and Disease 103. Vitamin D and Tuberculosis 104. Vitamin D and Adaptive Immunology in Health and Disease 105. Vitamin D and Innate Immunity 106. Vitamin D and Diabetes 107. Vitamin D and Multiple Sclerosis 108. Vitamin D and Inflammatory Bowel Disease 109. Psoriasis and other Skin Diseases

Section XII. Therapeutic Applications and New Advances 110. Sunlight protection by vitamin D compounds 111. Vitamin D, Cardiovascular Disease and Hypertension 112. Vitamin D, Acute Respiratory Infection, and Asthma/COPD 113. Vitamin D and Muscle Performance in Athletes 114. Vitamin D: Presence and Function in the Eye 115. Adult vitamin D deficiency and adverse brain outcomes 116. Vitamin D in Pregnancy and Lactation: Moving into the Future 117. Vitamin D and Critically Ill ICU Patients