Main description:

Attention deficit hyperactivity disorder (ADHD) is a common neurobehavioral disorder affecting 5-10% of children and adolescents and 3% of adults. Attention Deficit Hyperactivity Disorder: From Genes to Patients aims to provide a comp- hensive, state-of-the-art overview of the critical aspects of ADHD, and hopefully will serve as a quick and up-to-date reference source for professionals with an int- est in ADHD. The book is divided into three major areas that follow an historical survey. The first group of chapters deals with current theories on the pathophysiology of ADHD, and focuses on neurotransmitters and the contributions and validity of animal m- els. The second section emphasizes the evaluation and treatment of patients with ADHD, from the day-to-day approach by the clinical psychologist to the more sophisticated anatomical and functional imaging strategies that have emerged in the last decade. In addition, chapters dealing with specific impairments, such as those pertaining to reading, social interaction, and working memory, are also included for more detailed analysis of these important aspects and their respective contributions to global functioning. The third and final section provides an expanded review on the pharmacotherapy of ADHD and the appropriate methods for selection of specific drugs for individual patients based on drug kinetics and gene expression. David Gozal, MD Dennis L. Molfese, PhD vii CONTENTS Dedication . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi 1 Historical Aspects of Attention Deficit Hyperactivity Disorder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Roscoe A. Dykman 2 Scanning the Genome for Attention Deficit Hyperactivity Disorder . . . . . . . . . . . . . . . . . . . . . . . . .

Contents:

Historical Aspects of Attention Deficit Hyperactivity Disorder
Roscoe A. Dykman

Scanning the Genome for Attention Deficit Hyperactivity Disorder
Aiveen Kirley

Dopamine Knockouts and Behavior
Davide Viggiano, Daniela Vallone, Lucia A. Ruocco, and Adolfo G. Sadile

The SHR as a Model of Attention Deficit Hyperactivity Disorder
Vivienne Ann Russell

The Roles of Norepinephrine and Serotonin in Attention Deficit Hyperactivity Disorder
Robert D. Oades

Intermittent Hypoxia During Sleep as a Model of Environmental (Nongenetic) Contributions to Attention Deficit Hyperactivity Disorder
Barry W. Row and David Gozal

The Psychological Evaluation of Attention Deficit Hyperactivity Disorder in School-Aged Children: A Clinical Approach Based on Recent Practice Guidelines
Dean W. Beebe

Executive Function
Martha Bridge Denckla

The Neuropsychology of Attention Deficit Hyperactivity Disorder: Validity of the Executive Function Hypothesis
Erik G. Willcutt, Kimberly Brodsky, Nomita Chhabildas, Michelle Shanahan, Benjamin Yerys, Ashley Scott, and Bruce F. Pennington

Attention Deficit Hyperactivity Disorder and Learning Disabilities
Stephen R. Hooper and Emily A. Williams

Selective Attention Deficits in Children With Attention Deficit Hyperactivity Disorder: A Review of Behavioral and Electrophysiological Studies
Lisa M. Jonkman

Working Memory in Children With Attention Deficit Hyperactivity Disorder
Jack Stevens

Developmental Underpinnings of the Association of Attention Deficit Hyperactivity Disorder and Its Subtypes to Neuropsychological and Academic Weaknesses
Tuija Aro, Margaret Semrud-Clikeman, Anne-Mari Lapvetelainen, and Heikki Lyytinen

Social Functioning of Children With Attention Deficit Hyperactivity Disorder
Hana Tur-Kaspa

Reading Disabilities in ChildrenWith Attention Deficit Hyperactivity Disorder
Juliana S. Bloom, Carlin J. Miller, Mauricio A. Garcia, and George W. Hynd

Attention Deficit Hyperactivity Disorder and the Brain: Evidence From Electrophysiological Studies
Alexandra P. Fonaryova-Key, Melissa Ferguson and Dennis L. Molfese

Anatomical and Functional Neuroimaging Studies of Children and Adolescents With Attention Deficit Hyperactivity Disorder
Jonathan C. Pfeifer, Melissa DelBello, and Scott Holland

State Regulation and Attention Deficit Hyperactivity Disorder
Jaap van der Meere

Sleep and Attention Deficit Hyperactivity Disorder
Louise M. O'Brien and David Gozal

Neuropsychological Performance in Adults With Attention Deficit Hyperactivity Disorder
Lisa Lee Weyandt

Psychostimulants in Attention Deficit Hyperactivity Disorder: Theoretical and Practical Issues for the Community Practitioner
Daniel F. Connor

Pharmacokinetic and Pharmacodynamic Drug Interactions: Methylphenidate, Amphetamine or Atomoxetine in Attention Deficit Hyperactivity Disorder
John S. Markowitz and Kennerly S. Patrick

Index