Main description:

Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems.

Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.

Contents:

1.Cells in the liver. Functions in health and disease. Fabio Marra, Maurizio Parola
2.Physiology of liver function. Jean Francois Dufour, Alexander Sendensky
3.Assessment of liver function in clinical practice Hamed Khalili MD, Lawrence S. Friedman MD, Barham Abu Dayyeh, MD
4.Physiology of the splanchnic and hepatic circulations. Gautam Mehta, Juan-Carlos Garcia-Pagan, Jaime Bosch
5.Fibrosis as main mechanism of chronic liver disease. Lars P. Bechmann, Scott L. Friedman
6.Stem cells in the liver Aiwu Ruth He, Arun Thenappan, Feras J Abdul Khalek, Lopa Mishra
7.The role of inflammatory mediators in liver failure Joan Claria, Marta Lopez-Parra, Esther Titos, Ana Gonzalez-Periz.
8.Genomics of the liver in health and disease Kostas Lazaridis, MD

PART II. EFFECTS OF LIVER FAILURE ON ORGAN SYSTEMS

9.Hepatic encephalopathy and alterations of cerebral function Juan Cordoba, Rita Garcia Martinez
10.Bacterial translocation and alterations of the digestive system Reiner Wiest
11.SIRS, bacterial infections and alterations of the immune system Rajiv Jalan,
12.Extracellular fluid volume regulation and renal function. Jens Henriksen,.
13.The heart in chronic liver failure. Hongqun Liu, Soon Woo Nam, Samuel S. Lee
14.Hemostasis abnormalities in chronic liver failure. Armando Tripodi,.
15.The systemic and splanchnic circulations., Yasuko Iwakiri Ph.D.
16.Liver microcirculation. Chittaranjan Routray, Vijay Shah
17.Angiogenesis in liver diseases. Manuel Morales-Ruiz, Sonia Tugues, Wladimiro Jimenez
18.Pulmonary alterations in chronic liver failure Michael J. Krowka MD, Aynur Okcay MD
19.Adrenal function in chronic liver failure Javier Fernandez,.

PART III. MANAGEMENT OF CHRONIC LIVER FAILURE

20.Antibiotic prophylaxis and management of bacterial infections. Joseph K. Lim, M.D., Puneeta Tandon, M.D., Guadalupe Garcia-Tsao, M.D.
21.Management of ascites and hyponatremia Andres Cardenas, Pere Gines
22.Management of renal failure. Vicente Arroyo, MD and Monica Guevara, MD
23.Therapy of Hemostasis abnormalities in chronic liver failure. Andrew Burroughs
24.Prevention and management of gastrointestinal bleeding. Juan G. Abraldes, Jaime Bosch, Juan Carlos Garcia-Pagan
25.Extracorporeal artificial liver support systems. Rafael Banares, Maria-Vega Catalina
26.Issues in transplantation of patients with chronic liver failure. Michael D. Leise, W. Ray Kim, Patrick S. Kamath
27.Management of chronic liver failure in the intensive care unit. Dr Andrew Slack, Dr Julia Wendon