Main description:

Over the past 2 decades, there has been a steady increase in knowledge associated with the clinical manifestations of cholestatic liver disease. In addition to a growing amount of information on the well-studied disorders of primary biliary cirrhosis and primary sclerosing cholangitis, there has been a rapid accumulation of data on less well-known but important topics such as overlap syndromes with autoimmune hepatitis, cholestatic variants of alcohol and viral disease, and cholestasis following liver transplantation. These emerging insights are complemented by further improvements of the diagnosis and management of cholestasis.

Based on these clinical situations, Cholestatic Liver Disease provides essential information for individuals involved in the care of patients affected by cholestatic liver disease. This groundbreaking text also supplies scientific updates from leading experts which relate to the clinical evaluation and management of cholestatic liver disorders, useful for both novice and practitioners alike. Among the topics discussed in this volume are PBC, PSC, overlap syndrome with autoimmune hepatits, sarcoid, lymphoma, cystic fibrosis, rheumatologic disease, and osteoporosis. Comprehensive and timely, Cholestatic Liver Disease is sure to be an indispensable reference for all those who work with cholestatic liver.

Feature:

Provides timely, useful information on the ever-expanding subject of cholestatic liver disease

Covers PBC, PSC, overlap syndrome and more

Emerging insights complimented by further improvements in diagnosis and management

Back cover:

Over the past 2 decades, there has been a steady increase in knowledge associated with the clinical manifestations of cholestatic liver disease. In addition to a growing amount of information on the well-studied disorders of primary biliary cirrhosis and primary sclerosing cholangitis, there has been a rapid accumulation of data on less well-known but important topics such as overlap syndromes with autoimmune hepatitis, cholestatic variants of alcohol and viral disease, and cholestasis following liver transplantation. These emerging insights are complemented by further improvements of the diagnosis and management of cholestasis.

Based on these clinical situations, Cholestatic Liver Disease provides essential information for individuals involved in the care of patients affected by cholestatic liver disease. This groundbreaking text also supplies scientific updates from leading experts which relate to the clinical evaluation and management of cholestatic liver disorders, useful for both novice and practitioners alike. Among the topics discussed in this volume are PBC, PSC, overlap syndrome with autoimmune hepatits, sarcoid, lymphoma, cystic fibrosis, rheumatologic disease, and osteoporosis. Comprehensive and timely, Cholestatic Liver Disease is sure to be an indispensable reference for all those who work with cholestatic liver.

Contents:

Chapter Titles Topics to Cover Author Information
1. Diagnosis of cholestasis Liver tests/antibodies
Cross-sectional studies
Liver biopsy
MRCP, ERCP, CT Cholangiogram, EUS Velimir Luketic, M.D.
Virginia Commonwealth University
804-828-4060-P
vluketic@hsc.vcu.edu
2. Drug-induced cholestasis Include herbal remedies
Jacqueline Laurin, M.D.
University of Maryland
410-328-1358-P
jlaurin@medicine.umaryland.edu
3. PBC Usual (overlap and recurrence after transplant covered elsewhere)
Cynthia Levy, M.D.
University of Florida
352-392-6002-P
levyc@medicine.ufl.edu
4. PSC Usual (overlap and recurrence after transplant covered elsewhere)
Risk of colon CA with IBD, colon CA post-transplant, and
cholangiocarcinoma Kelly Burak, M.D.
University of Calgary
403-210-9363
kwburak@ucalgary.ca
5. Overlap Syndrome with autoimmune hepatitis PBC/AIH
PSC/AIH Alastair Smith, M.B.
Duke University Medical Center
919-681-4044-P
alastair.smith@duke.edu
6. Rare causes of cholestasis (genetic disorders) BRIC, Dubin Johnson
Byler, Rotor, etc. Konstantinos Lazaridis, M.D.
Mayo Clinic
507-284-1006-P
lazaridis.konstantinos@mayo.edu
7. Cholestatic variants of alcohol, viral disease Alcohol
Hepatitis (viral) Jeffrey Crippin, M.D.
Washington University
314-454-8160-P
jcrippin@wustl.edu
8. Cholestasis from systemic disorders Sarcoid, lymphoma, granulomatous
disease, cystic fibrosis, rheumatologic diseases David Kaplan, M.D.
University of Pennsylvania
215-823-5800-P
dakaplan@mailmed.upenn.edu
9. Complications of cholestasis Osteoporosis
Pruritus
Lipids Marlyn Mayo, M.D.
University of Texas Southwestern
214-648-3444-P
marlyn.mayo@utsouthwestern.edu
10. Cholestasis post transplantation Drugs, strictures, viral disease,
recurrent cholestatic liver disease Timothy McCashland, M.D.
University of Nebraska
402-559-8859-P
tmccashland@unmc.edu