Main description:

The book discusses the recent progress in understanding the therapeutic targets for gallbladder cancer to provide opportunities for research and for developing innovative strategies that may enhance the benefit of conventional chemotherapy.

The book focuses on identifying candidate molecules and the overall status of the targeted therapies available for gallbladder cancer, as there is an urgent need to discover new molecular targets that can guide the emergence of new treatment strategies to improve patient outcomes and act as biomarkers for the early detection of diseases. Recently, new treatment therapeutics targets for gallbladder cancer patients have been identified and the field is evolving rapidly.

The book is relevant for the clinical researcher, surgeon, scientist and academician.

Contents:

Section I:Surgical Management, Adjuvant Chemotherapy and Palliative Chemotherapy in gallbladder cancer

Ch1. Surgical Management of gallbladder cancer patients
Ch2. Chemotherapy treatment for gallbladder cancer
Ch.3 Adjuvant therapy for the gallbladder cancer treatment
Ch4. Neo-adjuvant chemotherapy in the gallbladder cancer treatment
Ch5. Radiotherapy for locally advanced or metastatic gallbladder cancerSection II: Targeted Therapies in gallbladder cancer

Ch6. Advanced gallbladder cancer treatment intends to target particular molecular pathways
Ch7. MicroRNA and its significance for the treatment of gallbladder cancer patients
Ch8. Long Non-coding RNAs of gallbladder cancer as developing molecular therapeutics
Ch9. HER2/neu therapy for gallbladder cancer treatment
Ch10. Targeting the EGFR pathways in carcinomas of the gallbladder treatment
Ch11. Anti-egfr therapy as a therapeutic option for galbladder cancer patients
Ch12. Targeting MAPK and mTOR pathways: a potent therapeutic for gallbladder cancer
Ch13. Galectin-9: a therapeutic agent for gallbladder cancer treatment

Section III: Clinical trials in gallbladder cancer treatment

Ch14. Effect of combination of gemcitabine and oxaliplatin with panitumum as first-line therapy for KRAS wild-type gallbladder cancer
Ch15. Effect of ONO-7579in antitumor efficacy against gallbladder cancer
Ch16. Study on the effect of sorafenib (SWOG 0514) in patients having metastatic gallbladder cancer
Ch17. A phase II study on the effect of gemcitabine and oxliplatin or gemcitabine and cisplatin in gallbladder cancer patients