Main description:

Within the last decade there have been a number of new and important areas of emphasis in HIV care and research, particularly in the context of brain involvement. Without question, clinical and research innovations in the modern era of the HIV pandemic warrant an update on HIV and the brain. Written by a panel of leading experts, "HIV and the Brain: New Challenges in the Modern Era" offers a clear picture of brain impairment associated with the virus with particular focus on three emerging areas including different genetic strains of the virus throughout the world, interactions between advanced age and HIV, and the impact of HIV on the brain in the context of chronic, long-term treatment with highly active antiretroviral therapy (HAART)."HIV and the Brain: New Challenges in the Modern Era" provides a comprehensive review of both basic science and clinical implications in these important areas of the disease. The text is of particular relevance to both research scientists and clinicians involved in HIV in the modern era.

Contents:

Chapter 1 Neurocognitive changes in HIV: Evolution of Treatment of HIV Infection. Erna Milunka Kojic, M.D. Charles Carpenter, M.D.Chapter 2Global incidence and epidemiology of the AIDS pandemic, distribution of HIV subtypes and epidemiology of Hepatitis C infection among HIV positive individuals.Karen T. Tashima, M.D., Aadia Rana, M.D.Chapter 3New Insights into HIV Neuropathogenesis.Tory P. Johnson, M.S., Avindra Nath, M.D.Chapter 4Neuropathological findings associated with long term HAART treatment.Ian. C. Anthony, Ph.D., Jeanne E. Bell, M.D.Chapter 5Biomarkers of HIV related Central Nervous System Disease.Bruce James Brew MBBS MD FRACP, Scott L. Letendre MDChapter 6Neuroimaging Among HIV Infected Patients: Current Knowledge and Future DirectionsDavid F. Tate, Ph.D., Jared Conley, B.S., Dominik Meier, Ph.D., Bradford Navia, M.D., Ph.D., Ronald Cohen, Ph.D., Charles R.G. Guttmann, M.D.Chapter 7The assessment of HIV-associated neurocognitive disorders: New challenges in the HAART eraChronic neuro-AIDS, long-term cognitive assessment, and new risk factorsLucette A. Cysique, Ph.D., Bruce J. Brew MBBS MD FRACPChapter 8The changing face of HIV-associated cognitive and neuropsychiatric disturbance.Ron Cohen, Ph.D.Chapter 9Youth with HIV/AIDS: Neurobehavioral ConsequencesSusannah Allison, Ph.D., Pamela L. Wolters, Ph.D., Pim Brouwers, Ph.D.Chapter 10Co-occurrence of HIV, Hepatitis C, and Substance Use Disorders: Effects on Brain Functioning.Raul Gonzalez, Ph.D., Phillip J. Quartana, Ph.D., Eileen M. Martin, Ph.D.Chapter 11The Functional Impact of HIV-associated Neuropsychological DeclineMatthew J. Wright, Ph.D., Ellen Woo, Ph.D., Terry R. Barclay, Ph.D., & Charles H. Hinkin, Ph.D.Chapter 12Adjunctive therapy for long-term support of cognitive impairmentJoshua T. Dearborn, M.A., Susan E. Maloney, M. A., Nicole Hicklin, M.A.Elizabeth M. Lane, B.A., Robert Paul, Ph.D.Chapter 13HIV-1 Genetic diversity and its biological significance.Michael M. Thomson, M.D., Ph.D.Chapter 14Opportunistic infections in the brain in developing countriesMarcus Tulius T Silva, M.D., M.Sc., Ph.D., Beatriz Grinsztejn, M.D., M.Sc., Ph.D.Chapter 15Impact of clade diversity on neuropsychological outcomesRobert Paul, Ph.D., Ned Sacktor, M.D., Lucette Cysique, Ph.D., Bruce Brew, M.D., Victor Valcour, M.D.Chapter 16The effects of aging on HIV diseaseRobert C. Kalayjian, M.D., Lena Al-Harthi, Ph.D.Chapter 17Neuropsychology of Healthy AgingMolly E. Zimmerman, Ph.D., Adam M. Brickman, Ph.D.Chapter 18Interactions between Advanced Age and HIV Cognitive ImpairmentVictor Valcour, M.D., Aaron McMurtray , M.D.