Main description:

This book sheds new light on "inducible" lymphoid organs (ILOs): antigen presentation sites that are generated de novo in peripheral tissues under various pathogenic conditions. Accomplished immunologists demonstrate that the physiological role of these ILOs is completely different from that of central lymphoid organs, i.e., the lymph nodes or spleen. In addition to the central organs, the ILOs are considered essential structures for the efficient elicitation of adaptive immune responses in lesions.

The respective chapters highlight examples from multiple sites, e.g. the skin, lung, intestinal tract, genital tract, the synovial membrane of the joints and artificial lymph nodes. Accordingly, readers will learn that ILO structure and function can vary substantially, depending on the context.

Presenting the results of the latest immunological research, the book offers a fascinating and insightful read for both scientists and clinicians in the areas of infectious and immune-associated diseases.

Contents:

Basic structure of the inducible lymphoid organs

[Now recruiting]

Title: Role of iBALT in respiratory immunity

Prof. Troy D. Randall, [Confirmed]

troyrandall@uabmc.edu

Division of Clinical Immunology & Rheumatology, UAB

Title: Inducible M cells in mucosal immunity

Professor David Lo, [Confirmed]

david.lo@medsch.ucr.edu

University of California, Riverside

Title: Role of iSALT in skin immunity

Gyohei Egawa and Kenji Kabashima

[Confirmed]

Title: Memory lymphocyte cluster in genital immunity

Dr. Norifumi Iijima, [Confirmed]

niijima@nibiohn.go.jp

National Institute of Biomedical Innovation, Health and Nutrition (NBIOHN)

Title: Ectopic lymphoid tissue in rheumatoid arthritis

Prof. Costantino Pitzalis, [Confirmed]

c.pitzalis@qmul.ac.uk

William Harvey Research Institute, Barts and the London School of Medicine

Title:Ectopic lymphoid structure in cancer

[Now recruiting]

Title: Artificial engineering of lymphoid organs

Dr. Takeshi Watanabe, [Confirmed]

tthta_w@icloud.com

Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University