Main description:

The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking-the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.

Contents:

Chapter 1_Significance of microbiome on human healthcare.- Chapter 2_Animal models for microbiome studies.- Chapter 3_Bioinformatics tools for analyzing microbiomes.- Chapter 4_Modulation of Systemic Immune Responses through genital, skin, and oral microbiota.-Chapter 5_Role of microbiome in development of immune system.- Chapter 6_Understanding the interplay between host immune-microbiome interactions.- Chapter 7_Overview on human gut microbiome and its role in immunomodulation.- Chapter 8_Cancer microbiome and immunotherapy: Understanding the complexity between microbes, immunity, and cancer.- Chapter 9_Dynamics of Respiratory Microbiome in lung dysbiosis.- Chapter 10_Microbiome Therapeutics: Emerging concepts and challenges.- Chapter 11_Intestinal Microbiome and Health.- Chapter 12_Macromolecule signalling mediating inflammation and immune system interaction.- Chapter 13_Microbiome-immune homeostasis and their involvement in cancer immunotherapy.- Chapter 14_Challenges and future prospects in the microbiome intervention in human health and disease.