Main description:

This volume aims at presenting the latest international research and discoveries in the neurocognitive aspects and complications in HIV/AIDS, and how this understanding can shape and inform how we think about clinical practice and patient care in HIV/AIDS as well as lead to a better understanding of the underlying neuropathogenesis.
The chapter, "Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders", of this book is available open access under a CC BY 4.0 license at link.springer.com

Contents:

I. Neuropathogenesis and Biomarkers.- New Potential Axes of HIV Neuropathogenesis with Relevance to Biomarkers and Treatment.- Neurocognitive Impairment and Associated Genetic Aspects in HIV Infection.- Inflammatory Mechanisms and Cascades Contributing to Neurocognitive Impairment in HIV/AIDS.- Neuroimaging Advances in Diagnosis and Differentiation of HIV, Comorbidities, and Aging in the cART Era.- II. Neurocognitive Impairments in Low-, Middle- and High-Income Countries - Incidence / Prevalence and Contexts.- Neurocognitive Complications of Pediatric HIV Infections.- Neurocognitive Complications of HIV Infection in Women: Insights from the WIHS Cohort.- Cultural Neuropsychology Considerations in the Diagnosis of HIV- Associated Neurocognitive Disorders.- Neurocognitive Complications of HIV Infection in Low-Income Countries.- Deep Phenotyping of HIV Neurocognitive Complications Among Individuals Residing in High-Income Countries.- Reliably Measuring Cognitive Change in the Era of Chronic HIV Infection and Chronic HIV-Associated Neurocognitive Disorders.- III. Comorbidities and Complications.- Geriatric Syndromes in People Living with HIV Associated with Ageing and Increasing Comorbidities: Implications for Neurocognitive Complications of HIV Infection.- Conceptualizing and Assessing Everyday Functioning in the Context of HIV-Associated Neurocognitive Disorders.- Neuropsychiatric Disorders, Emotional Disturbances, and Their Associations with HIV-Associated Neurocognitive Disorder.- Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders.- HIV-Associated Neurocognitive Disorder (HAND): Relative Risk Factors.- IV. Screening, Interventions and Clinical Management.- Screening for HIV-Associated Neurocognitive Disorders: Sensitivity and Specificity.- Behavioral and Physical Activity Interventions for HAND.- Targeting HIV-Related Neurocognitive Impairments with Cognitive Training Strategies: Insights from the Cognitive Aging Literature.- Clinical Treatment Options and Randomized Clinical Trials for Neurocognitive Complications of HIV Infection: Combination Antiretroviral Therapy, Central Nervous System Penetration Effectiveness, and Adjuvants.