Main description:

Thanks to advances in Anti-Retrovial Drugs (ARTs), HIV is treatable and those who have the disease are often able to lead a normal life. However, as a chronic (and incurable) infectious disease, HIV positive patients are susceptible to neuropsychiatric complications. These complications reduce the quality of life for the individual and exponentially increases the cost of medical care and medications to treat both conditions. Neuropsychiatric Complications of HIV: A Challenging Health Concern examines these neuropsychiatric complications prevalent in those who are HIV positive, providing clinical correlation, translational significance, and details guides to neurocognitive assessment, brain imaging, and related neuropharmacology.

Written for clinicians, researchers, and students working with HIV and AIDS, the book begins with the biology of HIV, a complete look at available ARTs and antibodies, as well as diagnostics tools for HIV. It continues on to the epidemiology of NeuroAIDs and the manifestations of it-cognitive deficits, dementia, depression, agitation, psychosis, and cognitive slowing.

Contents:

1. HIV and its Biology
2. Anti-Retroviral Drugs
3. HIV and Antibodies: The Catch 22
4. Diagnostic Tools for HIV
5. NeuroAIDS
6. NeuroAIDS: An Epidemological Perspective
7. Neurology of HIV
8. Dementia in AIDS Patients
9. NeuroAIDS: A Neurocognitive Assessment
10. NeuroAIDS: Brain Imaging
11. Neuropathology of NeuroAIDS
12. Neuropharmacology and NeuroAIDS
13. CNS: Entry of HIV
14. HIV Associated Dementia: Viral Loads and its Correlation
15. NeuroAIDS: Contribution of Microglia
16. NeuroAIDS: Contribution of Astrocyles
17. NeureoAIDS: Role of Blood Brain Barrier
18. NeuroAIDS: Role of Cytokines
19. BBB and Neuroinflammation
20. NeuroAIDS: Role of Monocyte and Macrophages
21. HIV Virotoxin
22. Genetics and Epigenetics of NeuroAIDS
23. Neuroinvasion by HIV
24. Antiretroviral Drug: Penetration to Brand