Main description:

Maurie Markman and a panel of distinguished clinicians and leading clinical investigators comprehensively review the current status of regional antineoplastic drug delivery in the management of malignant disease. These authorities present a critical analysis of both the rationale and limitations of regional therapy and discuss potential clinical trials designed to explain the effectiveness of this method of therapy in special settings. Their presentations describe many exciting and innovative strategies for using regional drug delivery in anticancer therapy, including coverage of such areas of special interest as colorectal, skin, lung, pancreatic, ovarian, and gastrointestinal cancers. Comprehensive and authoritative, Regional Chemotherapy: Clinical Research and Practice offers surgical and medical oncologists and clinical cancer investigators a gold-standard review of the current role and future development of this increasingly powerful weapon in the battle against cancer.

Contents:

Principles of Regional Antineoplastic Drug Delivery, Maurie Markman. Intrahepatic Chemotherapy for Metastatic Colorectal Cancer, Nancy E. Kemeny and Omar T. Atiq. Regional Hepatic Arterial Infusion Chemotherapy for Hepatic Colorectal Metastases, Robert J. Pelley. Regional Chemotherapy of Melanoma, Mary S. Brady and Daniel G. Coit. Isolated Limb Perfusion for Malignant Melanoma and Soft Tissue Sarcoma, Joseph M.
Klausner, Dina Lev-Chelouche, Subhi Abu-Abeid, and Mordechai Gutman. Lung Perfusion for Treatment of Metastatic Sarcoma to the Lungs, David Liu, Michael Burt, and Robert J. Ginsberg. Regional Chemotherapy of Cancer of the Pancreas, James H. Muchmore and Jyoti Arya. National Cancer Institute Experience with Regional Therapy for Unresectable Primary and Metastatic Cancer of the Liver or Peritoneal Cavity, H. Richard Alexander, David L. Bartlett, and Steven K. Libutti. Surgical Considerations in Intraperitoneal Chemotherapy, Donald W. Wiper and Alexander W. Kennedy. Memorial Sloan-Kettering Cancer Center Experience with Intraperitoneal Chemotherapy of Ovarian Cancer, Richard R. Barakat and David R. Spriggs. Southwest Oncology Group Experience with Intraperitoneal Chemotherapy of Ovarian Cancer, David S. Alberts, Dava J. Garcia, Emily Fisher, and P. Y. Liu. Intraperitoneal Biologic Therapy for Ovarian Cancer, John C. Elkas, Oliver Dorigo, and Jonathan S. Berek. Intraperitoneal Therapy with Fluoropyrimidines in the Treatment of Ovarian and Gastrointestinal Cancers, Franco M. Muggia, Tamar Safra, Susan Jeffers, Agustin Garcia, and Susan Groshen. Cytoreductive Surgery and Intraperitoneal Chemotherapy for Peritoneal Surface Malignancies, Paul H. Sugarbaker. Memorial Sloan-Kettering Cancer Center Experience with
Intraperitoneal Chemotherapy for Gastric Cancer, Eileen O'Reilly and David P. Kelsen. Regional Therapy for Gastric Cancer with and without Peritoneal Metastasis by Intraperitoneal Hyperthermic Chemoperfusion, Shigeru Fujimoto and Makoto Takashi. Intraperitoneal Chemotherapy in Management of Peritoneal Mesothelioma, Maurie Markman. Intravesical Therapy for Superficial Bladder Cancer, Kerry L. Kilbridge and Eric A.
Klein. Principles of Intrathecal Chemotherapy, Glen Stevens and David M. Peereboom. Regional Chemotherapy for Meningeal Involvement with Breast Cancer, Beth A. Overmoyer. Regional Chemotherapy for Treatment and Prophylaxis of Meningeal Lymphoma, Brad Pohlman. Regional Chemotherpay for the Treatment and Prophylaxis of Meningeal Leukemia, Matt E. Kalaycio. Index