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Arthritis Research
Volume 2: Methods and Protocols
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Main description:

Here is a compendium of data pertinent to the methods and protocols that have contributed to both recent advances in molecular medicine in general as well as to molecular basis of rheumatic disease in particular. This two-volume work collects the contributions of leaders in the field who cover such exciting and cutting edge topics as imaging and immunohistochemistry, analysis of cartilage and bone catabolism, immunobiology, and cell trafficking.


Contents:

Arthritis: Methods and Protocols, Volume II
Andrew P. Cope, PhD

I. Immunobiology

1. Phenotypic Analysis of B Cells and Plasma Cells
Henrik E. Mei, Taketoshi Yoshida, Gwendowlin Muehlinghaus, Falk Hiepe Thomas Dorner, Andreas Radbruch and Bimba F. Hoyer

2. Detection of Antigen Specific B Cells in Tissues
Marie Wahren-Herlenius and Stina Salomonsson

3. Single Cell Analysis of Synovial Tissue B Cells
Hye-Jung Kim and Claudia Berek

4. Tracking Antigen Specific CD4+ T Cells with Soluble MHC Molecules
John A. Gebe and William W. Kwok

5. Analysis of Antigen Reactive T Cells
Clare Alexander, Richard C. Duggleby, Jane C. Goodall, Malgosia K. Matyszak, Natasha Telyatnikova
and J.S. Hill Gaston

6. Identification and Manipulation of Antigen Specific T Cells with Artificial Antigen Presenting Cells
Eva Koffeman, Elissa Keogh, Mark Klein, Berent Prakken and Salvatore Albani

7. Analysis of Th1/Th2 T Cell Subsets
Alla Skapenko and Hendrik Schulze-Koops

8. Analysis of the T Cell Receptor Repertoire of Synovial T Cells
Lucy Wedderburn and Douglas J. King

9. The Assessment of T Cell Apoptosis in Synovial Fluid
Karim Razza, Dagmar Scheel-Toellner, Janet M. Lord, Arne N. Akbar, Christopher D. Buckley and Mike Salmon

10. Assay of T Cell Contact Dependent Monocyte-Macrophage Functions
Danielle Burger and Jean-Michel Dayer

11. Phenotypic and Functional Analysis of Synovial Natural Killer Cells
Nicola Dalbeth and Margaret F. C. Callan

12. Identification and Isolation and Synovial Dendritic Cells
Allison R Pettit, Lois Cavanagh, Amanda Boyce, Jagadish Padmanabha, Judy Peng and Ranjeny Thomas

II. Animal Models of Arthritis

13. The Use of Animal Models for Rheumatoid Arthritis
Rikard Holmdahl

14. Collagen Induced Arthritis in Mice
Richard O. Williams

15. Collagen Induced Arthritis in Rats
Marie M. Griffiths, Grant W. Cannon, Tim Corsi, Van Reese and Kandie Kunzler

16. Collagen Antibody Induced Arthritis (CAIA)
Kutty Selva Nandakumar and Rikard Holmdahl

17. Arthritis Induced with Minor Cartilage Proteins
Stefan Carlsen, Shemin Lu and Rikard Holmdahl

18. Murine Antigen-Induced Arthritis
Wim van den Berg, Leo A. B. Joosten, and Peter L.E.M. van Lent

19. Pristane Induced Arthritis in the Rat
Peter Olofsson and Rikard Holmdahl

20. The K/BxN Mouse Model of Inflammatory Arthritis: Theory and Practice
Paul Monach, Kimie Hattori, Haochu Huang, Elzbieta Hyatt, Jody Morse1, Linh Nguyen, Adriana Ortiz-Lopez, Hsin-Jung Wu, Diane Mathis, and Christophe Benoist

21. Analysis of Arthritic Lesions in the Del1 Mouse: A Model for OA
Anna-Marja Saamanen, Mika Hyttinen and Eero Vuorio

III. Application of New Technologies to Define Novel Therapeutic Targets

22. Gene Expression Profiling in Rheumatology
Tineke C.M.T. van der Pauw Kraan, Lisa G.M. van Baarsen, Francois Rustenburg, Belinda Baltus, Mike Fero and Cornelis L. Verweij

23. Differential Display Reverse Transcription-Polymerase Chain Reaction (DDRT-PCR) to Identify Novel Biomolecules in Arthritis Research
Manir Ali and John D. Isaacs

24. Two-Dimensional Electrophoresis of Proteins Secreted from Articular Cartilage
Monika Hermansson, Jeremy Saklatvala and Robin Wait

25. Mapping Lymphocyte Plasma Membrane Proteins: A Proteomic Approach
Matthew J. Peirce, Jeremy Saklatvala, Robin Wait and Andrew P. Cope

26. In Vivo Phage Display Selection in the Human/SCID Mouse Chimera Model for Defining Synovial Specific Determinants
Lewis Lee, Toby Garrood and Costantino Pitzalis

27. Adenoviral Targeting of Signal Transduction Pathways in Synovial Cell


PRODUCT DETAILS

ISBN-13: 9781588299185
Publisher: Springer (Humana Press Inc.)
Publication date: July, 2007
Pages: 460
Weight: 852g
Availability: Available
Subcategories: Genetics, Orthopaedics and Fractures
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